research Chemotherapy and Cutaneous Drug Reactions
Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
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research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research Fabrication of Astaxanthin-Loaded Electrospun Nanofiber-Based Mucoadhesive Patches With Water-Insoluble Backing for the Treatment of Oral Premalignant Lesions
The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.
research Subungual Melanocytic Lesions: A Histopathological Review
Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
research Efficacy of Topical Nanoemulsion (NB-002) for the Treatment of Distal Subungual Onychomycosis: A Randomized, Double-Blind, Vehicle-Controlled Trial
NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.
research Sox9 Expression in Canine Epithelial Skin Tumors
Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
research Psoriatic Onychopachydermoperiostitis: Improvement with Etanercept
Etanercept improved symptoms of a specific type of psoriatic arthritis in a patient who didn't respond to other treatments.
research Dermatologic Diseases and Pregnancy
Pregnancy can cause normal skin changes, including darkening of certain areas, nail changes, vascular changes, and breast changes like stretch marks.
research Inflammatory and Non-Melanocytic Tumoral Pathology of the Nail
The document concludes that understanding nail anatomy is key for diagnosing nail diseases, early signs of nail melanoma may allow for less aggressive treatment, and specific genetic mutations are important in thyroid cancer prognosis and treatment.
research Cutaneous and Mucosal Side Effects of New Anticancer Drugs: EGF-R Inhibitors, Tyrosine Kinase Inhibitors, and Mitotic Spindle Stabilizers
New cancer drugs can cause skin side effects like rashes, dry skin, hair changes, and nail problems.
research Can You Diagnose Hair Loss (Non-Scarring Alopecia)
Non-scarring hair loss can be diagnosed with two 4mm punch biopsies, one cut vertically and the other transversely.
research Hair and Nail Diseases in the Elderly Population
Older adults commonly experience hair loss and nail disorders due to aging and health changes, affecting their quality of life.
research Genetics of Thyroid Lesions Updated
RET mutation is important in familial medullary thyroid carcinoma, and BRAF mutation in papillary thyroid carcinoma is linked to more aggressive cancer and higher death rates.
research Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects
Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.
research Results of 60-Second Timed Hair Counts in Women Aged 20–60 Years
The 60-second timed hair count is a reliable and simple way to measure hair shedding at home, showing older women tend to shed more hair than younger women.
research Alopecia Areata Is Associated With MICA and an Extended HLA Haplotype
Certain genes are linked to the risk of developing Alopecia Areata.
research Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study
Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.
research Beau's Lines
Beau's lines and hair loss in a patient were linked to severe stress on the body.
research Topical Treatment of Androgenetic Alopecia with Spironolactone
Topical spironolactone effectively treats hair loss in women.
research British Hair and Nail Society
Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
research Systemic Antifungals: Overview, Applications, and Costs
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Telogen Effluvium and Associated Incidence of Abnormal Serum Ferritin, Zinc, 25-Hydroxy Vitamin D, and Thyroid-Stimulating Hormone
Vitamin D deficiency is common in temporary hair loss, and stress is often a suspected cause.
research Safety and Efficacy of Tavaborole (AN2690), a Novel Boron-Based Molecule, in Three Phase II Trials for the Topical Treatment of Toenail Onychomycosis
Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.
research Robotically Assisted Follicular Unit Extraction in Surgical Hair Restoration
Robotic-assisted hair transplant is effective and less painful, but needs more evaluation for long-term results.
research The Features of Onychomatricomas on In Vivo Reflectance Confocal Microscopy
Reflectance confocal microscopy can noninvasively diagnose onychomatricoma by showing unique features different from healthy nails or nail fungus.
research Evaluation of the Activity of Laser Light Doses Compared to an Inactive Control Dose on Ex Vivo Hair Growth
Low-level laser therapy increased hair growth compared to no treatment.
research A Randomized, Placebo- and Active-Controlled, Parallel-Group, Multicenter, Investigator-Blinded Study of Four Treatment Regimens of Posaconazole in Adults with Toenail Onychomycosis
Posaconazole is a promising new treatment for toenail fungus.
research Hair Care Practices in Different Populations: What Makes a Difference?
Social or cultural norms, not hair type, more likely influence how often people wash their hair.
research Journal Watch
A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
research Regulation of Hair Growth
The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.