February 2022 in “Research Square (Research Square)” This study found that high TSPEAR expression in colorectal cancer was associated with poor prognosis and correlated with various tumor and immune-related factors.
April 2023 in “Journal of Investigative Dermatology” This study found that occlusive dressings on mouse wounds eliminated wound-induced hair neogenesis by upregulating mechanotransduction, which promotes fibrosis, and suppressing Wnt signaling involved in regeneration.
November 2024 in “Journal of Investigative Dermatology” Serotonin helps wounds heal faster.
3 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that inhibiting YAP signaling in skin wounds leads to regenerative repair with active Trps1 and Wnt signaling, contrasting the typical fibrotic scarring process.
13 citations
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July 2012 in “International Journal of Trichology” In this study, the varied phenotype of trichothiodystrophy was highlighted, with findings of distinctive hair shaft abnormalities and a wide range of multisystem issues, including neurologic and urologic disorders.
May 2022 in “Reactions Weekly”
3 citations
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December 2021 in “Frontiers in endocrinology” In this study, a novel DCAF17 gene mutation was identified in a Chinese family, suggesting a potential role in pancreatic β cell dysfunction and diabetes development in Woodhouse-Sakati syndrome.
August 2018 in “Journal of The American Academy of Dermatology” Patients with multiple superficial venous thrombosis are at greater risk for serious complications like cancer and recurrent blood clots.
3 citations
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May 2018 in “Psychiatry and Clinical Psychopharmacology” In this report, an 18-year-old female with trichotillomania was successfully treated using the glutamate modulator n-acetylcysteine.
May 2022 in “Experimental dermatology” In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.
6 citations
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January 2015 in “Il Giornale di Chirurgia” This report describes two cases of hair tourniquet syndrome involving the thumb and toe, which were successfully treated without complications.
October 2023 in “International Journal of Cosmetic Science” In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.
January 2022 in “Research Square (Research Square)” This study found that elevated TSPEAR expression in colorectal cancer was associated with poor overall prognosis and correlated with tumor infiltrating immune cells, suggesting its potential as a predictive biomarker.
36 citations
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January 2014 in “The Journal of Sexual Medicine” This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.
In this study with mice, simultaneous inactivation of Smad4 and PTEN genes led to rapid development of invasive forestomach squamous cell carcinomas, mirroring human esophageal SCCs.
October 2023 in “Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy” This study introduces three spectrophotometric techniques for accurately determining finasteride and tadalafil in their combined pharmaceutical form, demonstrating their sustainability, sensitivity, and suitability for quality assurance, alongside a dissolution study following FDA guidelines.
77 citations
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February 2017 in “Stem Cell Reports” This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.
This article describes an improved trichophytic closure technique for hair restoration surgery, achieving nearly invisible donor scars in over 95% of patients, but emphasizes tailoring the method to individual patient characteristics.
May 2025 in “Health Science Reports” This study reported that applying Serum WS Biotin, a water-soluble form of D-Biotin, daily for 3 months significantly reduced hair shedding and increased hair strength in volunteers with moderate to excessive hair shedding, while showing good skin compatibility.
35 citations
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September 2011 in “The Journal of Dermatology” This article discusses the trichoscopic diagnosis of temporal triangular alopecia, but reports no new clinical results.
October 2025 in “The Sri Lanka Journal of Dermatology” This report describes two cases of toxic epidermal necrolysis with long-term mucosal scarring and liver issues, underscoring the complexities of recovery and chronic effects of this severe drug reaction.
13 citations
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November 1985 in “International Journal of Dermatology” This study examined patients with trichostasis spinulosa and identified distinct differences in the distribution and microscopic appearances of lesions compared to keratosis pilaris and eruptive vellus hair cysts.
September 2012 in “African Journal of Urology” This review describes the clinical features of testosterone deficiency syndrome in aging men but reports no new experimental findings, highlighting the need for clinical recognition and treatment of TDS.
This study found that WISP-1 plays a key role in ligamentum flavum fibrosis through the Hedgehog-Gli1 pathway, with cyclopamine showing potential to reduce fibrosis effects in a rabbit model.
1 citations
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July 2020 in “International journal of radiology & radiation therapy” This study found that VMAT hair-sparing WBRT partially preserved scalp hair at four weeks post-treatment without compromising symptomatic disease control in the short term, but reduced hair loss did not improve quality of life.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study demonstrated that both DKK2 and SOSTDC1 are necessary for normal timing of the first catagen phase in mice hair growth cycles.
15 citations
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June 2019 in “Journal of Neuroendocrinology” This study found that isoallopregnanolone reduced stress-induced tic-like behaviors and sensorimotor gating deficits in a mouse model of Tourette syndrome, suggesting potential therapeutic properties comparable to existing treatments like haloperidol and finasteride.
July 2020 in “Indian journal of sexually transmitted diseases and AIDS” This article highlights the importance of an algorithmic approach to manage multiple opportunistic infections in HIV-infected patients due to the risk of drug interactions and complications, but reports no new clinical results.
6 citations
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January 2019 in “Dermatology Research and Practice” This study found that ocular and mucocutaneous sequelae are common in SJS/TEN survivors, with exposure to sulfadoxine and severe acute ocular involvement identified as significant risk factors for ocular sequelae.
April 2012 in “Informa Healthcare eBooks” Temporal triangular alopecia is a lifelong condition with hairless patches on the side of the head that may be present from birth.