research Three Isostructural Solvates of Finasteride and Their Solid-State Characterization
Three new finasteride solvates found, change forms under different drying conditions.
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research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Whole-Cell Bioprocessing of Human Fetal Cells for Tissue Engineering of Skin
Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Progestogens in Menopausal Hormone Therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Hair Follicles as a Critical Model for Monitoring the Circadian Clock
Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
research Vesicles: Potential Nano Carriers for the Delivery of Skin Cosmetics
Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
research Liposomes in Cosmeceuticals
Liposomes could improve how skin care products work but are costly and not very stable.
research Niosomes as a Promising Carrier for Topical Drug Delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Extractives of Cercidiphyllum Japonicum Twigs: Isolation and Structural Elucidation of a New Galloylflavonol Glycoside, Anomeric Tannins and Flavonoids
Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research Traditional Uses, Phytochemistry, Pharmacology, Toxicity and Clinical Application of Traditional Chinese Medicine Cynoglossum Amabile: A Review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
research Structural Characterization of Cyclosporin A, C, and Microbial Bio-Transformed Cyclosporin A Analog AM6 Using HPLC–ESI–Ion Trap-Mass Spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
research Application of Metal Organic Frameworks-Based Functional Composite Scaffolds in Tissue Engineering
Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
research The Pioneer Factor SOX9 Competes for Epigenetic Factors to Switch Stem Cell Fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
research Drug Repositioning: Current Approaches and Their Implications in the Precision Medicine Era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Comparison of Saccharina Japonica–Undaria Pinnatifida Mixture and Minoxidil on Hair Growth Promoting Effect in Mice
The L-U mixture promotes hair growth as effectively as minoxidil.
research Potential Medical Uses of Cannabigerol: A Brief Overview
CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
research Perspectives of Alopecia Behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype
The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
research Isolation And Identification Of Endophytic Actinobacteria From Citrullus Colocynthis And Their Antibacterial Properties
Certain bacteria from the Citrullus colocynthis plant may be a new source of antibiotics to fight drug-resistant diseases.