186 citations
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February 2013 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
179 citations
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April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
96 citations
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January 1997 in “Clinics in Dermatology” Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
83 citations
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October 2008 in “Current Opinion in Chemical Biology” The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.
69 citations
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December 2016 in “Facial plastic surgery” Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.
66 citations
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July 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
66 citations
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February 2006 in “Photochemical & photobiological sciences” We don't fully understand how sunlight damages different types of hair.
59 citations
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July 1972 in “Biochemistry” Transamidases help form strong crosslinks in hair proteins, crucial for hair strength.
53 citations
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September 2004 in “American journal of medical genetics. Part C, Seminars in medical genetics” Mutations in keratin genes cause cell fragility and various skin disorders.
38 citations
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December 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
36 citations
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December 2006 in “Medical Care Research and Review” The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.
28 citations
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April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
26 citations
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May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
25 citations
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November 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
21 citations
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January 2018 in “Livestock science” Nellore cattle have genetic variations linked to their adaptation to tropical environments.
17 citations
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September 2005 in “International Journal of Dermatology” African hair is more fragile due to its unique shape and internal structure.
16 citations
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April 2018 in “European Journal of Endocrinology” Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
16 citations
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April 2015 in “Forensic science international” The hair of two ancient Chilean mummies is well-preserved and contains high levels of heavy metals.
15 citations
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October 2016 in “Journal of dermatological treatment” Proper hair care can prevent and stop hair breakage in people with acquired trichorrhexis nodosa.
15 citations
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July 2002 in “Clinical and Experimental Dermatology” Hair microscopy is useful for diagnosing certain hair loss conditions but has limitations and must be interpreted carefully.
13 citations
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May 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
13 citations
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March 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
13 citations
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January 1991 in “Dermatology” Minoxidil helps hair growth in people with monilethrix without side effects.
12 citations
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July 2015 in “British journal of dermatology/British journal of dermatology, Supplement” Curly hair breaks due to mechanical damage and environmental factors, not chemical makeup, and needs ongoing care to prevent breakage.
10 citations
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September 2020 in “Biopolymers” Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.
9 citations
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August 2018 in “Acta biomaterialia” Eyelash curvature is linked to the thickness of the cuticle layer at the root.
8 citations
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June 2023 in “Advanced functional materials” Tunable structured metal oxides show promise for various medical treatments due to their versatility and cost-effectiveness.
8 citations
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March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
7 citations
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June 1994 in “International journal of biochemistry/International Journal of Biochemistry” The document discusses various skin disorders and new therapeutic approaches.
6 citations
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May 2020 in “Nutrients” Eating fewer calories may slow skin aging and improve skin health through various biological changes.