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Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Zinc is effective for treating various skin conditions, including warts and acne.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Probiotic bacteria improved skin and hair health in aged mice.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.