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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

No cure for female pattern hair loss, but various effective treatments exist.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Some systemic treatments work for nail psoriasis but can have serious side effects.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.