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Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Oral contraceptives may cause hair loss in women.

Certain drugs change freshwater snail shells to a "banana" shape.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Androgens increase EPO production, finasteride doesn't significantly impact it.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

The document concludes that new treatments for skin conditions are complex but effective, including spironolactone for female hair loss and propranolol for infantile hemangiomas.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Androstanediol glucuronide is a reliable marker for hirsutism in women.