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Effective PCOS treatments require targeting specific signaling pathways.

Certain changes in the SHBG gene may increase the risk of PCOS in Iraqi women.

Low vitamin D levels can significantly contribute to hair loss, especially in women aged 35-45. Correcting these levels early may help prevent and treat this condition.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Dutasteride and finasteride cause kidney damage, with dutasteride being more harmful.

Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.

Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Muscles can make their own androgens, which may help muscle growth.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.

Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.

Women with PCOS are more likely to develop kidney stones, especially those with certain PCOS types.

Androgens play a key role in causing alopecia by changing the hair growth cycle.

Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Postmenopausal women with past hirsutism or irregular periods have more heart and lung diseases.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.