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The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Finasteride effectively blocks enzyme causing male pattern baldness.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Bee venom helps hair grow and may work better than some common treatments.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Sebocytes play a key role in controlling androgen levels in human skin.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.