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Using 5-alpha reductase inhibitors may increase the risk of mild depression.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Some common medications can harm male fertility, but many effects can be reversed.

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.