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Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Finasteride exposure harms tadpole reproduction and hormone balance.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

Muscles can make their own androgens, which may help muscle growth.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Tetrathelmis tetrathele extract may help prevent hair loss and improve scalp health.

Finasteride negatively affects fish reproduction and gonadal development.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

The exact causes of baldness are not fully understood, limiting treatment options.

Finasteride potentially treats hair loss by reducing DHT production.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.