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Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Melatonin affects mouse skin and may regulate skin functions.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Low vitamin D levels are common in people with Alopecia Areata.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

Using rodents for research shows that health problems in the womb can cause diseases later in life.