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In this study, the NADES extract of mangkokan leaves (Polyscias scutellaria) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with a total flavonoid content measured at 4.944 mgEQ/gSimplisia using the disc diffusion method.

In this case series, four adults developed severe, disabling multisymptom illness potentially linked to fluoroquinolone use, which persisted and progressed even after discontinuation of the drug.

This study identifies five compounds, including gemcitabine and methylene blue, that inhibit SADS-CoV and suggests their potential for developing antiviral drugs against future outbreaks.

This review discusses ongoing and past trials for novel acne treatments, focusing on topical agents with potential sebosuppressive, antimicrobial, or anti-inflammatory effects, without reporting new clinical results.

This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.

This paper describes a new scalable synthesis method for Dutasteride, highlighting its potential for large-scale commercial production.

This review examines the role of thiopurines in managing inflammatory bowel diseases like ulcerative colitis and Crohn's disease, and reports no new clinical results, emphasizing the need for more studies on thiopurine withdrawal scenarios.

This chapter reviews various synthetic methods for creating pharmacologically active diazines, particularly focusing on pyrimidines, and discusses their potential in clinical applications. It also examines novel synthetic strategies that improve the drug-like qualities and safety profiles of these compounds.

This case report describes a 38-year-old patient with trichomycosis axillaris, successfully treated with shaving, 3% erythromycin cream, and clotrimazole powder.

This presentation highlighted future directions in acne care, emphasizing the roles of topical and oral antibiotics, as well as skin microbiome studies. It also described how clascoterone targets androgen receptors in hair follicles and sebaceous glands to reduce sebum production.

Tavaborole is a safe and effective toenail fungus treatment, with the 5% solution being the best option.

This article discusses dermatologic adverse events associated with topoisomerase inhibitors and anthracyclines, such as alopecia and hand-foot syndrome, but reports no new clinical results.

This research presentation explored the roles of mammalian multi-copper ferroxidases in iron homeostasis and highlighted new insights into their functions, including non-iron-related ones, while discussing arsenic's role in microbial warfare as a potential antibiotic.

The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.

This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.

This study found that combining prodigiosin and essential oil from Thuja orientalis leaves showed a synergistic effect against the 3rd larva stage of Cx. pipiens, significantly reducing acetylcholine esterase activity and altering midgut pH, compared to untreated larvae.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

This study found that a novel thiohydantoin derivative, 3a, effectively inhibited androgen receptor activity in LNCaP cells and showed promising in vivo results by reducing testosterone-induced prostate changes, outperforming finasteride in mitigating prostate index and histopathological alterations.

In this study, early treatment with nitazoxanide, ivermectin, or hydroxychloroquine, combined with azithromycin, was associated with reduced hospitalizations, respiratory complications, and deaths in early-stage COVID-19 patients compared to untreated controls.

This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.

This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.

In this retrospective study at Hiroshima University, methotrexate effectively controlled ocular inflammation in Japanese patients with non-infectious uveitis over 6 to 24 months, but a high incidence of adverse effects indicates careful monitoring and dose adjustments are important.

This study concluded that combining the Shumin treatment instrument with oral doxycycline provides better clinical outcomes for rosacea than combining red light therapy with doxycycline, while both regimens improved quality-of-life scores and reduced Demodex counts.

In this study, Deplanque et al. (2016) explored doxycycline's role in preventing erlotinib-induced folliculitis in patients with non-small-cell lung cancer, highlighting skin toxicity as a common side effect that can affect patient adherence to treatment.

This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.

This case report describes a 61-year-old woman with Sjögren's syndrome who experienced multiple episodes of aseptic meningitis linked to trimethoprim-sulfamethoxazole and trimethoprim use.

This study documented a case of Dipylidium caninum infection in a 4-month-old female dog, effectively treated with a deworming medication, resulting in significant improvement and no worms detected after five days. Routine deworming and maintaining hygienic conditions are recommended to prevent reinfection and transmission.