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research Prospective randomized study of sexual function in men taking dutasteride for the treatment of androgenetic alopecia
In a randomized study, men treated with dutasteride for androgenetic alopecia experienced sexual adverse events at twice the rate of those on placebo during 24 weeks, but these events were mild, moderate, and resolved after treatment.
research Hyperandrogenism from an Ovarian Interstitial-Cell Tumor in an Alpaca
In this case study, an 8-year-old female Huacaya alpaca displaying male behavior was diagnosed with an ovarian benign interstitial (Leydig) cell tumor, indicated by elevated testosterone levels.
research Testosterone Treatment in Women – An Overview
This review discusses the impact of testosterone therapy on postmenopausal women's sexual function and well-being but notes a lack of long-term safety studies and debates on defining androgen insufficiency.
research Comprehensive transition of care for polycystic ovary syndrome from adolescence to adulthood
research A Phase 1, Open‐Label Study of the Pharmacokinetics of Ritlecitinib in Children Aged 6–12 Years With Alopecia Areata
In this study, ritlecitinib was generally well tolerated in pediatric alopecia areata patients aged 6 to <12 years, with no severe or serious adverse events reported, and the drug's pharmacokinetic parameters were successfully characterized.
research Daily subcutaneous testosterone for management of testosterone deficiency
This retrospective analysis reported significant increases in testosterone levels in men with testosterone deficiency using the Daily Subcutaneous Testosterone method combined with hCG and anastrozole, indicating its potential as a treatment option.
research Telogen effluvium caused by COVID-19 in Elmhurst, New York: report of a cohort and review
This study suggests that COVID-19-related telogen effluvium resembles other forms of telogen effluvium, and many patients may experience hair regrowth within several months.
research Case 1: Severe acne – not just skin deep
This case report describes a 10-year-old girl with advanced puberty signs and resistant acne, highlighting potential early-onset puberty with associated growth patterns.
research Impact of time to surgical treatment in Merkel cell carcinoma: Surveillance, Epidemiology, and End Results–based population study
research Safety and Effectiveness of a Novel Hyaluronic Acid Gel for Lip Augmentation
In this double-blind study, a novel hyaluronic acid gel for lip augmentation was found to be as effective and safe as a commercially available gel, with similar adverse event profiles and high patient and investigator improvement ratings over six months.
research Case Report: Hypopituitarism Masquerading As Failure to Thrive in a 75‐Year‐Old Woman
This report describes a case of a 75-year-old woman whose diagnosis of hypopituitarism led to significant weight gain and improved physical function with treatment, highlighting the potential for overcoming frailty when investigating underlying causes in elderly patients.
research Dermatological, Trichological and Quality of Life Consequences of GLP ‐1 Receptor Agonist‐Mediated Weight Loss: A US Cross‐Sectional Survey
This study observed that dermatological and hair changes, like skin sagging and hair shedding, commonly occur early during weight loss with GLP-1 receptor agonists, highlighting the need for tailored dermatological care alongside treatment.
research Aesthetic Medicine and Aesthetic Health Psychology: Toward an Integrative Framework for Patient-Centered Care
This paper proposes integrating Aesthetic Health Psychology into aesthetic medicine to enhance ethical practice and improve patient-reported outcomes by using a comprehensive, interdisciplinary framework.
research Cardiac tamponade due to minoxidil use: a case report and review of the literature
In this case report, an 81-year-old male with chronic kidney disease developed cardiac tamponade while on minoxidil for hypertension, highlighting the rare but serious risk of pericardial effusion from this medication and emphasizing the need for vigilant monitoring, especially in vulnerable patients.
research Excluded at the Root: Health Insurance Discrimination Against Hair Loss Conditions
research Part II. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?
In this narrative review, researchers examined common misconceptions and questions about creatine monohydrate, addressing issues such as its potential effects on muscle benefits without exercise, interactions with caffeine, inflammatory properties, safety during pregnancy, and effects on adolescents, among others.
research Addressing Autoimmune and Immune-mediated Skin Disease Burden in Women
This review highlights the urgent need for increased research and policy support for autoimmune and immune-mediated skin diseases, which are on the rise and disproportionately affect women's health in the United States, suggesting a focus on gender and socioenvironmental factors.
research Structural Characterization and Ligand Specific Protein Interactions of Androgen Receptor
This study found that AR-007 degrades faster and has a stronger association with hsp70 than AR-014, suggesting it is less stable when bound to the androgen receptor.
research Eflornithine Cream Combined with Laser Therapy in the Management of Unwanted Facial Hair Growth in Women
This study reported that eflornithine cream, when used with laser hair removal, leads to faster reduction of unwanted facial hair in women and is similarly safe compared to the cream alone.
research In the quest to stymie time, will laboratory data stand up in man?
This review discusses various theories and mechanisms of aging, highlighting recent findings on the hormone Klotho, which increased lifespan in mice in laboratory settings, but notes a potential trade-off with human health risks.
research Extracellular ATP in Plants. Visualization, Localization, and Analysis of Physiological Significance in Growth and Signaling
This study observed that extracellular ATP is present in Medicago truncatula and correlates with regions of active cell growth, suggesting its integral role in plant development.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
This review discusses the significance of IL-1 family cytokines in skin inflammation and pathology, emphasizing their interactions with microbes and potential therapeutic applications, but reports no new clinical results.
research Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases—A Focus on Psoriasis and Lupus erythematosus
This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.
research Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature
In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review
This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.
research Vitamin D3 metabolites and analogues in the treatment of scalp psoriasis
This study found that calcitriol, tacalcitol, and calcipotriol ointments achieved complete clearance of scalp psoriasis in 45%, 35.2%, and 17.6% of patients, respectively, with minimal side effects.
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
This article reviews the immunometabolic mechanisms linking polycystic ovary syndrome to infertility and stresses the need for interdisciplinary approaches to treat PCOS-related fertility issues; it reports no new clinical results.
research Responses of hair follicle gene expression to the cold season and growth promotion technology in Angus and Brahman cattle
This study found that hair follicle gene expression varies between Angus and Brahman cattle and responds to growth-promoting treatments, which may reflect breed differences in adaptability to cold stress.
research CURRENT UNDERSTANDING OF VITILIGO: A COMPREHENSIVE LITERATURE REVIEW
This review highlights advancements in vitiligo treatment, noting improved diagnostic techniques and the emergence of targeted therapies like Janus Kinase inhibitors, which may offer more effective management of this complex autoimmune skin disorder.