3 citations
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October 2021 in “Dermatologic Therapy” This study demonstrated that PRP treatment improved hair metrics in androgenetic alopecia, with the dermapen method proving more effective than the point-by-point technique for specific hair growth indicators.
June 2025 in “Archives of Dermatological Research”
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
September 2022 in “Dermatologic Therapy” This article is a correspondence that discusses platelet-rich plasma application methods for androgenic alopecia but reports no new clinical results.
September 2025 in “Polymer Korea” In this study, a parsley-derived n-hexane fraction formulated into a coconut oil-based nanoemulsion demonstrated significant hair regrowth comparable to 3% minoxidil, with near-complete coverage by day 17, suggesting potential as a topical hair growth treatment.
1 citations
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June 2025 in “Therapeutic Delivery” This article reviews microneedle technology as a transdermal drug delivery platform without presenting new clinical results, emphasizing its engineered microstructure arrays for enhanced penetration.
25 citations
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May 2020 in “Progress in Organic Coatings” This study found that bio-based waterborne polyurethanes derived from castor oil may offer effective hair-styling performance without skin irritation and appear to be safer for the environment compared to traditional hair sprays.
1 citations
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July 2005 in “CRC Press eBooks” This paper discusses topical drug delivery targeting the pilosebaceous unit for skin diseases and cosmetic purposes, emphasizing formulation choice and drug physicochemical properties but reports no new findings.
July 2003 in “Hair transplant forum international” This article discusses needle-stick injury risks in hair restoration practices and reports no new research findings; the authors emphasize the potential for disease transmission and safety concerns.
January 2025 in “Journal of Controlled Release” This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.
46 citations
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May 2006 in “Laser Physics” In this study, particles similar in size to keratin cells were surprisingly found to penetrate more efficiently into hair follicles due to a possible pumping effect from moving hairs.
5 citations
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May 2020 in “Pharmaceutical Research” This study found that short durations of heat and specific chemical penetration enhancers significantly improved the delivery of finasteride to human scalp skin and hair follicles.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” This study reports the successful formulation of a stable herbal hair serum with Catharanthus roseus extract and other ingredients, noting it has a suitable pH, consistency, and stability, suggesting potential effectiveness as a natural alternative for hair care pending further clinical trials.
January 2012 in “Lume (Universidade Federal do Rio Grande do Sul)” January 2025 in “Theseus (Ammattikorkeakoulujen)” In this study, a Finnish functional ingredient called SpruceSugar™ was found to slightly reduce scalp oil (sebum) and water loss compared to a control over four weeks, although differences were not statistically significant. Both study groups experienced similar improvements in scalp moisture.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a new triamcinolone acetonide serum combined with a microneedling device, showing promise for treating alopecia areata by targeting hair follicles in a less invasive, patient-friendly way with confirmed drug solubility, compatibility, and safety.
This study developed a novel protocol that demonstrated improved localized delivery of minoxidil to eyebrow application sites with minimal runoff, compared to a control formulation.
162 citations
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study introduces a novel non-invasive method called "differential stripping" to quantify the penetration of topically applied substances into hair follicles.
January 2018 in “Journal of analytical, bioanalytical and separation techniques” 3 citations
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September 2018 in “Current Drug Delivery” This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.
This summary highlights in vitro and in vivo experiments showing that nano-sized liposomes with bound polihexanide penetrate hair follicles more effectively and may extend antiseptic effects longer than conventional polihexanide solutions.
2 citations
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January 2012 in “Journal of The Chilean Chemical Society” This study developed and validated a precise RP-HPLC-PDA method for estimating finasteride in bulk and tablet forms, suitable for quality control use.
2 citations
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May 2016 in “Hair transplant forum international” This article discusses the limitations in the design or mechanism of hair implanter pens and reports no new findings.
22 citations
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April 2018 in “Pharmaceutics” This special issue reviews current challenges and innovative solutions for enhancing the penetration of topical formulations for human skin, reporting no new results.
October 2025 in “Journal of the Korean Society of Cosmetology” This study found that applying a hair mist with dandelion extract before heat perming improved wave efficiency, tensile strength, and hair cuticle condition compared to a base mist or no pretreatment, demonstrating the extract's protective effects against heat damage.
April 2025 in “Journal of Advances in Medical and Pharmaceutical Sciences” This review highlights the potential of spanlastics, a new type of drug delivery system, to enhance drug administration by offering better deformability and stability compared to other nanocarriers, potentially improving targeted drug delivery across various applications.
34 citations
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July 2010 in “Expert Opinion on Drug Delivery” This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.
1 citations
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November 2017 in “JFL : Jurnal Farmasi Lampung” In this study, researchers found that hair tonic formulations containing Nothopanax scutellarium extract enhanced hair growth in male rabbits over 21 days, with the 25% concentration showing comparable effects to a minoxidil-based positive control.
January 2024 in “AIP conference proceedings”