8 citations
,
January 2013 in “Australasian journal of dermatology” This review examines trichodysplasia spinulosa, a rare virus-linked skin condition in immunosuppressed individuals, noting its clinical features and highlighting antiviral treatment efficacy, without new clinical results.
8 citations
,
June 1995 in “Helvetica Chimica Acta” This article outlines the synthesis of spiro[cyclohexane‐1,2′‐[2 H ]indene] derivatives similar to known steroid 5α‐reductase inhibitors, but it does not report experimental findings.
8 citations
,
April 1988 in “Journal of endocrinological investigation” This study found that topically administered spironolactone in healthy volunteers resulted in no detectable systemic absorption or changes in related hormone levels over 72 hours, indicating local effect only.
7 citations
,
January 1990 This study found that spironolactone at doses of 75 or 100 mg per day did not improve hair density after six months in women with female pattern hair loss, suggesting that higher doses may be necessary.
6 citations
,
April 2013 in “Journal of Investigative Dermatology” This study reports that spironolactone use was associated with a decreased risk of developing rosacea compared to other diuretics, particularly in current users without previous androgenic skin disease diagnoses.
6 citations
,
July 2023 in “Spine Surgery and Related Research” This article reviews the potential of PRP as a treatment for spinal pain but calls for established use guidelines and protocols before wider clinical adoption, with no new clinical results reported.
6 citations
,
November 1993 in “Contact dermatitis” Spironolactone in anti-acne cream can cause allergic skin reactions in some people.
6 citations
,
January 1984 in “PubMed” This study found that spironolactone reduced androgenic hormones in hirsute women but had only marginal effects on hair growth, making it no more advisable than other therapies.
5 citations
,
December 2020 in “Journal of The American Academy of Dermatology” This study observed objective improvement in androgenetic alopecia in 5 out of 6 adolescent girls treated with 2.5 mg oral minoxidil and spironolactone, and reported no adverse effects.
5 citations
,
April 2016 in “Proceedings of the Latvian Academy of Sciences. Section B, Natural, Exact and Applied Sciences” This study fabricated a polyamide fiber containing amber particles and characterized its potential for textile applications, noting that the chemical structure of amber remained unchanged after grinding and integration.
4 citations
,
January 2025 in “Annals of the New York Academy of Sciences” This review explores how spiny mice (Acomys spp.) exhibit unique regenerative healing abilities, with findings indicating that these rodents use specialized injury response mechanisms and proregenerative pathways to enhance tissue repair and regeneration compared to scar-forming mammals.
4 citations
,
May 2024 in “Rapid Communications in Mass Spectrometry” This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.
4 citations
,
March 2024 in “Journal of the American Academy of Dermatology” Spironolactone for skin issues rarely causes low blood pressure.
4 citations
,
January 2022 in “Dermatologic Therapy” This review discusses the use of spironolactone for common skin diseases like acne and its potential role in daily clinical practice but presents no new clinical results.
4 citations
,
December 2021 in “Journal of The American Academy of Dermatology” This study reported a significant increase in the use of spironolactone for treating acne and hidradenitis suppurativa in female adolescents, noting a 2- to 3-fold rise in prescriptions and suggesting improved tolerance compared to adults, though its efficacy in adolescents is less pronounced.
4 citations
,
September 2018 in “Rendiconti lincei. Scienze fisiche e naturali” This study concluded that spikenard specimens in Renaissance Italian herbaria are attributed to Nardostachys jatamansi, a plant used in traditional medicine and cosmetics.
4 citations
,
January 2018 in “Cosmetics” This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.
4 citations
,
January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.
4 citations
,
August 2015 in “PloS one” This study found that whisker follicle stem cells transplanted to injured spinal cords in mice contributed to healing and unexpectedly grew hair at the injury site.
4 citations
,
October 2009 in “International Journal of Endocrinology and Metabolism” This study found that both Diane 35 plus spironolactone and Diane 35 plus finasteride were equally effective and safe for treating hirsutism and acne in Indian women over a 12-month period.
4 citations
,
November 1996 in “European journal of endocrinology” This study found that spironolactone therapy may reduce hair width in prepubertal girls with simple hypertrichosis, though its long-term efficacy and safety remain uncertain.
3 citations
,
March 2024 in “Discover Applied Sciences” In this study, researchers found that a protein-enriched cream made from Spirulina platensis improved the physical structure of natural hair, as evidenced by more intact and smoother cuticles compared to a control cream without protein, suggesting its potential for hair care applications.
3 citations
,
July 1990 in “Acta dermato-venereologica” This case report describes hair regrowth in a 73-year-old male who had been bald for decades, which might be associated with the antiandrogenic effects of spironolactone.
3 citations
,
September 2025 in “PLoS ONE” In this study, researchers used the FAERS database to identify rare adverse events potentially linked to spironolactone, finding new safety signals such as a possible association with male endometriosis, suggesting further research is needed to understand these findings better.
3 citations
,
August 2024 in “Molecular Biology Reports” This study found that the lncRNA018392, responsive to melatonin, accelerates cell proliferation in cashmere goats by recruiting the transcription factor SPI1 to upregulate the nearby gene CSF1R, which may explain the molecular mechanisms of cashmere growth.
3 citations
,
March 2024 in “International Journal of Women’s Dermatology” This study observed that spironolactone improved hidradenitis suppurativa in over 80% of female patients at 3 and 6 months, with no significant differences in response due to menstrual flares or polycystic ovarian syndrome, but mild adverse events were reported.
3 citations
,
August 2020 in “Nutrition Journal” This study found that spinach-derived thylakoid supplementation, combined with a calorie-restricted diet, led to more significant improvements in weight loss and insulin sensitivity in obese women with PCOS than calorie restriction alone.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This report shares the authors' experience using spironolactone for treating acne in a PCOS clinic, but provides no new clinical results.
3 citations
,
January 2016 In this study, NuMA's microtubule-binding domain was found to be crucial for correct spindle orientation and skin differentiation, with its loss leading to neonatal lethality in mice.
3 citations
,
February 2013 in “Journal of Medicinal Plants Research” This study found that both crude Spirulina extract and C-phycocyanin showed similar effects on keratinocyte proliferation and wound healing, with C-phycocyanin performing better in tissue regeneration in vivo on the 7th day.