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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Oestrogens are key for bone growth during puberty in both boys and girls.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Finasteride effectively treats baldness but may cause sexual side effects.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Finasteride effectively treats hidradenitis suppurativa for most patients.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.