April 2023 in “Journal of Investigative Dermatology” This study found that dimethyl fumarate improved delayed wound healing in Il36rn-/- mice by reducing neutrophil extracellular trap formation and oxidative stress.
21 citations
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August 1987 in “Archives of Dermatology” This communication reports previously unreported side effects, severe bullous dermatosis and onycholysis, in three patients undergoing high-dose methotrexate and leucovorin calcium therapy, impacting their chemotherapy schedules.
2 citations
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February 2022 in “Journal of Pharmacy and Pharmacology” In this study, two methotrexate-loaded liquid crystal formulations for topical application showed immunomodulatory effects and induced skin changes in mice with imiquimod-induced psoriasis.
10 citations
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April 1964 in “Journal of the American Geriatrics Society” This article reviews triamcinolone acetonide as an intramuscular long-acting steroid therapy for dermatologic disorders but reports no new clinical results.
60 citations
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June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
February 2026 in “International Journal of Clinical Dermatology” In this study, an 8-year-old girl with dermatomyositis and extensive calcinosis showed complete clearance of calcinosis and good disease control after treatment with a combination of corticosteroids, methotrexate, hydroxychloroquine, pamidronate, and intravenous immunoglobulin.
July 2024 in “Journal of Investigative Dermatology” PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.
17 citations
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November 2009 in “Dermato-endocrinology” This study found that a series of three monthly courses of medium-dose prednisolone pulse therapy was effective and well tolerated in most patients with active, multifocal alopecia areata but not in those with totalis/universalis.
July 2004 in “Journal of Clinical Oncology” This study found that therapeutic isolated limb perfusion with melphalan for in-transit melanoma metastases resulted in a high response rate but was associated with some systemic toxicity, including nausea, vomiting, and transient bone marrow depression.
November 2015 in “Ankara Medical Journal” This study concluded that weekly 5 mg folate supplementation is adequate for preventing methotrexate toxicity in rheumatoid arthritis patients, with no observed advantage to higher daily dosing after six months.
July 2004 in “Journal of Clinical Oncology” This study found therapeutic isolated limb perfusion with melphalan to be effective for in-transit melanoma metastases on a limb, with a high response rate and transient systemic toxicity.
5 citations
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January 2021 in “Daru” This case report highlights a rare instance of severe multi-organ involvement following a single dose of methotrexate for ectopic pregnancy, requiring intensive care but ultimately successfully treated with leucovorin and supportive care.
January 2026 in “Frontiers in Pharmacology” This study suggests that cedrol may improve mitochondrial function, gut microbiota, and intestinal barrier integrity, indicating its potential value in treating inflammatory bowel disease.
45 citations
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May 2002 in “International Journal of Dermatology” This case report describes a patient with systemic lupus erythematosus who developed multiple dermatofibromas while on long-term prednisone therapy.
July 2013 in “Our Dermatology Online” In this case study, an 11-year-old boy with extensive alopecia areata showed 80% hair regrowth after six months of treatment with methylprednisolone despite initial lack of response to topical therapies.
September 2007 in “대한피부과학회지” This study found that high dose methylprednisolone therapy may stop the progression of and promote hair regrowth in patients with acute diffuse alopecia areata.
6 citations
,
December 2022 in “Anais Brasileiros de Dermatologia”
February 2026 in “Scientific Reports” This preclinical study found that Mesenchymal Stem Cell-derived Conditioned Media formulations were safe and effective in rat and mouse models for treating chemotherapy- and radiation-induced oral mucositis, demonstrating improved tissue regeneration and healing, most notably at higher concentrations.
81 citations
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February 2000 in “Anti-cancer drugs” In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.
June 2016 in “Annals of the rheumatic diseases” This study found that methotrexate, when administered according to current recommendations, effectively manages rheumatoid arthritis for many patients in Poland, although regular monitoring is necessary due to possible adverse effects.
18 citations
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February 2006 in “Brain & development” This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.
1 citations
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January 2015 in “Annals of Dermatology” This case report describes a 52-year-old woman who developed retiform purpura after using cocaine likely adulterated with levamisole, highlighting the need for levamisole detection in such cases.
4 citations
,
May 2018 in “Journal of Neuro-Ophthalmology” This review describes the evolution of treatments for relapsing multiple sclerosis, highlighting that while newer potent monoclonal agents can potentially achieve disease remission, they also pose moderate to severe adverse event risks that healthcare providers must understand.
407 citations
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January 2008 in “Cochrane Database of Systematic Reviews” This review found that glucocorticoid corticosteroids can improve muscle strength and function in boys with Duchenne muscular dystrophy in the short term, but they are associated with significant short-term adverse effects.
This phase Ib study found that combining pegylated liposomal doxorubicin and pembrolizumab was well-tolerated and effective, with durable antitumor responses and a median survival of over two years in heavily pretreated ER-positive metastatic breast cancer patients.
5 citations
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January 2016 in “European Journal of Dermatology” Suplatast tosilate successfully treated a woman's systemic sclerosis symptoms.
5 citations
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November 2023 in “The Journal of Dermatology” This study found that anifrolumab effectively reduced disease activity and allowed for corticosteroid tapering in patients with systemic lupus erythematosus at Kanazawa University Hospital.
1 citations
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July 2021 in “Health & Medical Journal” This case report describes a 29-year-old man with systemic lupus erythematosus who responded well to pulse-dose methylprednisolone treatment.
This study provides insights into systemic lupus erythematosus patients' experiences with Anifrolumab, highlighting improvements in symptoms and health-related quality of life, despite ongoing daily life impacts.
2 citations
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September 2022 in “Annals of Oncology” This study observed that MIRV improved gastrointestinal symptoms and other quality of life measures in patients with platinum-resistant ovarian cancer compared to chemotherapy.