June 2021 in “Pakistan Journal of Medical and Health Sciences” This study found no association between the type of baldness, stress levels, and smoking status among male residents of Lahore.
This review discusses the role of norepinephrine release and protein kinase C activation in the development of benign prostatic hypertrophy, suggesting potential targets for new therapies, but it reports no new clinical results.
April 2011 in “The FASEB Journal” This study found that profilin1 protein significantly accelerated wound healing in transgenic mice by reducing wound size and enhancing vascularization and cell migration compared to nontransgenic and 88R/L mice.
March 2022 in “International Journal of Trichology” This review found a significant association between smoking and androgenetic alopecia, but notes a lack of studies on whether quitting smoking can improve hair loss.
12 citations
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August 2015 in “Plastic Surgery” This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.
11 citations
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October 2005 in “Toxicological Sciences” In this study, mouse skin exposed to cigarette smoke condensate exhibited increased epidermal thickness and ODC expression, with some changes persisting after exposure ended, suggesting potential for tumor promotion and measurement discrimination.
3 citations
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January 2021 in “Postepy Dermatologii I Alergologii” Yes, smoking damages your skin.
1 citations
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September 2025 in “PLoS ONE” This study observed that in mouse fetuses, reticular contraction by actomyosin is involved in dermal regeneration, and differences in actin and α-SMA localization may determine the switch between regeneration and scar formation, suggesting potential insights for wound regeneration therapy.
1 citations
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January 2024 in “Egyptian Dental Journal /Egyptian Dental Journal” This study observed that injecting minimally cross-linked hyaluronic acid with PDO smooth threads in female patients with dry, cracked lips led to significant improvements in lip texture, elasticity, and reduced fissure depth, effects that lasted up to nine months with additional booster injections.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers formulated and evaluated an herbal hair smoothing cream containing natural ingredients like aloe vera and coconut oil, reporting significant improvements in hair smoothness, softness, shine, and manageability without irritation, suggesting it as a safer alternative to traditional hair straightening products.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a formulated herbal hair smoothing cream using ingredients like aloe vera and coconut oil improved hair texture, such as smoothness and shine, without irritation, offering a safer alternative to conventional products.
November 2024 in “Benha Journal of Applied Sciences” In this study, the researchers explored how the loss of structural integrity in hair follicles due to reduced α-SMA expression in the vertex area may contribute to androgenetic alopecia.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” This study examined the vasorelaxant effects of two similar alkaloids, chloroquine and cinchonine, in a model of smooth muscle contractions induced by phenylephrine. Results are not reported in the abstract.
Patient history is key in diagnosing hair loss types.
102 citations
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January 2003 in “Dermatology” This review discusses the potential link between smoking and hair loss and suggests that raising awareness about this association could enhance anti-smoking education efforts.
41 citations
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March 2007 in “Journal of dermatological science” This study found that oral administration of l-cystine with vitamin B6 effectively prevents environmental cigarette smoke-induced alopecia in mice by reducing hair bulb cell apoptosis.
7 citations
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September 2020 in “Journal of Cosmetic Dermatology” This study found that the prevalence of androgenetic alopecia was significantly higher among smokers compared to nonsmokers, though the severity wasn't linked to smoking intensity.
5 citations
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January 2021 in “Skin appendage disorders” This review summarizes evidence suggesting that smoking is associated with alopecia and premature hair graying, with smokers showing higher prevalence than nonsmokers.
4 citations
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December 2014 in “Annals of neurology” This editorial discusses the rationale and limited evidence for "medical marijuana," suggesting that THC, an FDA-approved alternative, may often be a more appropriate choice for clinical use.
August 2025 in “Tobacco Induced Diseases” This study reported that active smokers, including e-cigarette and hookah users, had worse skin quality with more wrinkles and pigmentation compared to ex-smokers and non-smokers, suggesting smoking negatively impacts skin health and may motivate cessation efforts.
January 2021 in “Hair therapy & transplantation” This study observed that male smokers aged 20 to 35 showed a higher prevalence of hair loss compared to nonsmokers, suggesting that smoking and its related chemicals may accelerate alopecia.
33 citations
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November 1994 in “Archives of Biochemistry and Biophysics” 24 citations
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January 2014 in “PubMed” This study found that young Indian smokers with hypertension, central obesity, diabetes mellitus, and metabolic syndrome show a higher risk for premature acute coronary artery disease compared to those without these conditions.
12 citations
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January 2002 in “Environmental and Molecular Mutagenesis” This study found that long-term smoking was associated with increased mitochondrial DNA deletions in hair follicles, especially among smokers with low plasma glutathione S-transferase activity.
9 citations
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April 2016 in “Cutaneous and ocular toxicology” This study found that Alpha Lipoic Acid may help reduce cigarette smoke-induced skin damage in rats by improving collagen structure and reducing markers of oxidative stress.
2 citations
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January 2007
December 2024 in “Deleted Journal” This review highlights that flaxseed, due to its high levels of antioxidants and essential fatty acids, may improve hair texture, reduce frizz, and support hair growth, though more clinical studies are needed to confirm the best formulations and effects.
May 1987 in “Inpharma (Balgowlah)” Topical minoxidil may slow hair loss but often doesn't lead to satisfactory hair regrowth and requires ongoing treatment.
3 citations
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September 2016 in “The Journal of Dermatology” This letter to the editor discusses the occurrence of alopecia areata, thyroiditis, and vitiligo in a Japanese patient with smoldering type adult T-cell leukemia/lymphoma, but it reports no new research findings.