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    Glossary Small Molecules

    low-weight compounds that easily enter cells to regulate processes

    Small molecules are low molecular weight organic compounds that can easily enter cells due to their small size. They are often used in medicine to regulate biological processes, including the treatment of diseases like cancer and alopecia, by interacting with specific proteins or enzymes within the body.

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    Research 30 of 1000+

    1. Small Molecule Treatments Improve Differentiation Potential of Human Amniotic Fluid Stem Cells Frontiers in Bioengineering and Biotechnology · 2021 · 11 citations
    2. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming Experimental and Molecular Medicine · 2018 · 19 citations
    3. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    4. Biologics and small molecules for patients with concomitant alopecia areata and vitiligo: A review International Journal of Dermatology · 2024
    5. Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles Pharmaceutical research · 2012 · 43 citations
    6. High-Throughput Screening for Discovering Small Molecules Capable of Increasing the Wnt/β-Catenin Signaling Pathway to Promote Hair and Nail Growth Research Square (Research Square) · 2024
    7. Green Regenerative Hydrogel Wound Dressing Functionalized by Natural Drug‐Food Homologous Small Molecule Self‐Assembled Nanospheres Advanced Functional Materials · 2021 · 47 citations
    8. Editorial: Crosstalk: skin cells and immune cells in inflammatory skin diseases Frontiers in Immunology · 2024 · 3 citations
    9. Editorial: Targeted immunological therapies in dermatology Frontiers in Medicine · 2024
    10. Novel immune mechanisms in androgenetic alopecia 2024
    11. Mechanisms of autophagy and their implications in dermatological disorders Frontiers in Immunology · 2024 · 6 citations
    12. A translational approach to improve therapeutics in atopic dermatitis and beyond The Journal of Immunology · 2025 · 4 citations
    13. A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment Orphanet Journal of Rare Diseases · 2025
    14. New small molecules in dermatology: for the autoimmunity, inflammation and beyond Inflammation Research · 2023 · 9 citations
    15. Sequential small-molecule therapy for lymphocytic cicatricial alopecia: A multicenter prospective cohort pilot study Journal of the American Academy of Dermatology · 2026
    16. Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024 Pharmaceuticals · 2025 · 8 citations
    17. A Paintable Small-Molecule Hydrogel with Antimicrobial and ROS Scavenging Activities for Burn Wound Healing Gels · 2024
    18. Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules 2019
    19. A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules Journal of Visualized Experiments · 2017 · 9 citations
    20. Reprogramming the wound microenvironment: identity remodeling strategies for fibroblasts, keratinocytes, and macrophages Frontiers in Immunology · 2026
    21. Targeting integrin pathways: mechanisms and advances in therapy Signal Transduction and Targeted Therapy · 2023 · 54 citations
    22. New developments in the molecular treatment of ichthyosis: review of the literature Orphanet journal of rare diseases · 2022 · 21 citations
    23. 1359 Hair growth is induced by blockade of macrophage-derived oncostatin M and downstream JAK-STAT5 signaling in hair follicle stem cells Journal of Investigative Dermatology · 2018
    24. Biologics and Small Molecules for Inflammatory Nail Disorders: A Narrative Review Indian Dermatology Online Journal · 2024 · 1 citations
    25. Small molecules facilitate single factor-mediated sweat gland cell reprogramming Military Medical Research · 2022 · 9 citations
    26. Small molecules and small molecule drugs in regenerative medicine Drug Discovery Today · 2013 · 51 citations
    27. Biologics and Small Molecule Targeted Therapies for Pediatric Alopecia Areata, Psoriasis, Atopic Dermatitis, and Hidradenitis Suppurativa in the US: A Narrative Review Children · 2024 · 8 citations
    28. Small Molecule Inhibitors and Inflammatory Skin Diseases Suez Canal University Medical Journal · 2018
    29. A Small Molecule Inhibitor Partitions Two Distinct Pathways for Trafficking of Tonoplast Intrinsic Proteins in Arabidopsis PloS one · 2012 · 35 citations
    30. Effective holistic characterization of small molecule effects using heterogeneous biological networks Frontiers in Pharmacology · 2023 · 11 citations