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This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.

This article reviews the role of LMNA gene mutations, particularly in Hutchinson–Gilford progeria syndrome, but does not report new experimental findings.

This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.

This study observed that exposure to heavy metal salts affected skin and hair morphology in mice, with lead acetate decreasing keratinocyte proliferation and zinc sulfate and sodium dichromate increasing it.

In this study using C57BL/6N mice, the researchers found that skin thickness, mast cell counts, and immunoreactive density of certain cytokines increased at various stages of hair follicle growth following depilation.

This study examined prenatal and postnatal development of rat skin, observing marked changes in epidermal thickness and collagen fiber distribution as the rats aged.

This study evaluated enhancers to improve skin absorption of topical cetirizine for androgenic alopecia treatment and found eucalyptus and Tween 80 most effective, while propylene glycol had the weakest effect.

In this study, maternal exposure to constant light significantly altered the neonatal skin structure in rabbits, associated with reduced maternal melatonin levels.

This study suggests that both age and photoexposure may decrease maximum viable epidermis thickness and impact the dermal-epidermal junction in women with Fitzpatrick skin types II-III.

This study found that disrupting Lm332 expression in mice changes keratinocyte genetic expression, alters cell shape, and disrupts epidermal homeostasis, despite some compensatory anchorage by hair follicle basal cells.

This article reviews current understanding of dermal fibroblasts' structure and function, highlighting their crucial role in connective tissue formation and repair, which is important for selecting effective treatments for age-related skin changes.

This article reviews historical reports of skin changes, such as pseudoacanthosis nigricans, associated with cholesterol-lowering drugs like triparanol and nicotinic acid, but presents no new clinical findings.

This review discusses changes in keratin structure or gene expression that result in various skin disorders and reports no new clinical findings.

This study found significant changes in gene expression related to skin structure and signaling pathways in AEC syndrome skin, offering new insights into the syndrome's molecular underpinnings.

This study identified genetic regions evolving at different rates in hairless mammals, suggesting that specific genomic changes may contribute to the evolution of hairlessness across various species.

In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.

This study observed that overexpression of the enzyme ODC in transgenic mice caused hair loss and skin changes similar to human papular atrichia, suggesting that ODC might be involved in a critical hair follicle function pathway.

This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.

This study found that fibroblasts from mature skin showed significantly reduced mechanical force production compared to young skin fibroblasts, suggesting age-related changes in cellular mechanical properties.

This review highlights that isotretinoin effectively treats acne by addressing its pathogenic mechanisms, although managing its teratogenic risk and side effects through structured monitoring is crucial for safe use.

This study successfully created a mouse model with conditional knockout of the p75 neurotrophin receptor gene in epidermis cells, with no significant changes in skin histomorphology observed.

This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.

This study examined the age-related changes in the dermal structure of goat skin, providing baseline data on its histomorphology, histochemistry, and histoenzymology.

This review discusses how acute exposures to environmental and internal stressors can quickly alter skin functions, leading to various dermatological symptoms, and calls for more research on these short-term effects.

This study found that enlarged facial pores in women show distinct microstructural alterations, including regular keratinocyte arrangement and irregular dermo-epidermal junctions, highlighting changes in skin tension linked to pore enlargement.

This study analyzed the molecular evolution and functional divergence of the Dkk gene family, finding accelerated evolution in Aves and Reptilia and identifying functional differences that may impact hair follicle development via Wnt signaling inhibition.

This paper reviews the diverse skin, nail, and hair changes caused by medications, highlighting hyperpigmentation, alopecia, and nail structural alterations, but reports no new data.

In this animal study, Hirudo verbana leech extract significantly improved hair follicle regeneration and accelerated wound healing in rats, demonstrating potential as a safe and effective agent for skin repair due to its bioactive compounds with regenerative and anti-inflammatory properties.

This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.

This study found that hyperbaric oxygen treatment in rats led to structural changes in epidermis and dermis, including decreased E-cadherin expression and increased connective tissue.