![A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study](/images/research/aa825844-d933-470b-8a09-3b046f6c4dd8/small/3257.jpg)
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660-690 / 1000+ results![A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study](/images/research/aa825844-d933-470b-8a09-3b046f6c4dd8/small/3257.jpg)
![Stem Cell Dynamics in the Hair Follicle Niche](/images/research/e8d4cefc-5211-4a11-85e2-672071fdcee3/small/19741.jpg)
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
![Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF](/images/research/42dd80b6-1553-4c99-b7e5-bb58c1b93926/small/4003.jpg)
research Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF
Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
![Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation](/images/research/00b1292e-18be-4167-a822-5045d5c98d3c/small/23218.jpg)
research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation
Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
![Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis](/images/research/eb8bd287-9ad0-41a3-8b86-28143128a9b8/small/19578.jpg)
research Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis
PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
![Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges](/images/research/5a9839a9-731b-46a5-a0e2-c6c719b3c326/small/18853.jpg)
research Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
![MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway](/images/research/872e88ad-c146-4882-b90a-c091c18228f0/small/18756.jpg)
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
![WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation](/images/research/58f1fd1f-9be1-4cd7-b49b-02922b81aa7d/small/18206.jpg)
research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
![A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression](/images/research/61b76ed7-99f3-4cdb-b4b5-b1626a0b4709/small/25188.jpg)
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
![A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity](/images/research/4fca6c7a-15bb-4b29-ac99-93890fc4043b/small/20447.jpg)
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
![An Integrative View of Mammalian Seasonal Neuroendocrinology](/images/research/f63bad11-ba3d-4e48-9ad6-c714367eae1a/small/34868.jpg)
research An Integrative View of Mammalian Seasonal Neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
![The Blastema and Epimorphic Regeneration in Mammals](/images/research/5e6f6d4c-dd95-4edf-8d45-76900a07276d/small/19484.jpg)
research The Blastema and Epimorphic Regeneration in Mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
![Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil](/images/research/9b618201-243f-435d-b3c5-4026266f96cd/small/2376.jpg)
research Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil
Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
![Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin](/images/research/28cf0a2d-a4f2-44a5-8692-b739dc540dcf/small/25733.jpg)
research Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin
Follistatin helps hair growth and cycling, while activin prevents it.
![Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control](/images/research/d315ac6e-099e-402e-adc0-fd8abc282571/small/34961.jpg)
research Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control
TRH stimulates human hair growth and extends the hair growth phase.
![Drug Discovery for Alopecia: Gone Today, Hair Tomorrow](/images/research/7e4bda3e-56f8-48a2-989b-41805c4beb6b/small/3558.jpg)
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
![Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation](/images/research/bf7038ca-20bf-4fb9-8d9a-a11ba432fe33/small/19932.jpg)
research Genetic Interplays Between Msx2 And Foxn1 Are Required For Notch1 Expression And Hair Shaft Differentiation
Msx2 and Foxn1 are both crucial for hair growth and health.
![Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression](/images/research/b3054228-f74c-44d7-89ab-efb71eba5c5f/small/25001.jpg)
research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression
Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
![Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert](/images/research/306b0076-cdc9-4056-a36e-a2e4bc9b5608/small/29567.jpg)
research Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert
A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.
![External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway](/images/research/658d08a5-2d6b-4994-b652-f699e2bf346e/small/34117.jpg)
research External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway
Light can turn on hair growth cells through a nerve path starting in the eyes.
![Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes](/images/research/1c13346f-b590-42db-9d04-8e53359548c8/small/13892.jpg)
research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
![Bacteria Induce Skin Regeneration via IL-1β Signaling](/images/research/6140b738-04c9-4fe0-b954-ba271813e9df/small/12666.jpg)
research Bacteria Induce Skin Regeneration via IL-1β Signaling
Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
![The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias](/images/research/d914861b-de3a-4a82-926a-e3d0e2ba6b62/small/25997.jpg)
research The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
![The Hairless Gene of the Mouse: Relationship of Phenotypic Effects with Expression Profile and Genotype](/images/research/e36101d0-9c14-4466-8605-d02429f1e1f3/small/20047.jpg)
research The Hairless Gene of the Mouse: Relationship of Phenotypic Effects with Expression Profile and Genotype
Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
![Premature Graying of Hair: Causes, Associations, and Treatments](/images/research/488b3b95-046c-4946-921d-78a102ba65ae/small/24529.jpg)
research Premature Graying of Hair: Causes, Associations, and Treatments
Premature graying of hair may suggest health issues and currently lacks effective treatments.
![Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia](/images/research/bcfc2b99-1eaa-465b-8749-b2abd072ad40/small/33044.jpg)
research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia
Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
![Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo](/images/research/766231e2-4f43-4b96-87f3-3f758749221e/small/19327.jpg)
research Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo
Lymphatic vessels are essential for hair follicle growth and skin regeneration.
![Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle](/images/research/dcddf810-e612-42d4-a887-3b1dd9b759e7/small/13563.jpg)
research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle
Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
![Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures](/images/research/5c51a35a-d30f-4c18-96ea-05bc9f99aea0/small/21816.jpg)
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures
Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
![Self-Assembling Peptide Hydrogel Scaffolds Support Stem Cell-Based Hair Follicle Regeneration](/images/research/abae7ab9-893b-4069-b1f9-a4e33c7e8c97/small/3897.jpg)
research Self-Assembling Peptide Hydrogel Scaffolds Support Stem Cell-Based Hair Follicle Regeneration
Peptide hydrogel scaffolds help grow new hair follicles using stem cells.