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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Applying a special compound can promote hair growth without harmful side effects.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The circadian clock influences the behavior and regeneration of stem cells in the body.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

TRH stimulates human hair growth and extends the hair growth phase.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.