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In this controlled registry study, 8 years of testosterone therapy in hypogonadal men led to a significant decrease in waist circumference, weight, and BMI compared to those without the therapy.

This study suggests that testosterone may reduce knee joint range of motion by acting on relaxin receptors in rats, while flutamide and finasteride counteracted this effect and increased receptor expression.

In this case report, a 37-year-old man with discoid lupus erythematosus experienced around 80% hair regrowth after treatment with a combination of oral and topical therapies.

In this study, four dogs with a novel skin disease showed clinical lesions involving verrucous, crusted papules and plaques, and responded variably to immunosuppressive therapy, suggesting an immune-mediated cause.

This study describes three adult dogs with sebaceous gland dysplasia, reporting that two showed moderate to marked improvement in symptoms with treatment, though ongoing management is required as the condition cannot be cured.

The document explains how hair is studied in forensics to identify its source and its role in criminal investigations.

This study observed that patients with androgenetic alopecia in a western Indian population had a significantly higher prevalence of metabolic syndrome compared to a matched control group, suggesting that individuals with this type of hair loss may benefit from screening for metabolic syndrome.

This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.

This review describes how male hypogonadism can lead to various skin and hair symptoms, as well as potential dermatological reactions to hormone treatments and reports no new clinical results.

Finasteride use may be linked to rare testicular tumor, but more research needed.

A man developed hair loss from testosterone treatment but improved with additional medication.

This case report describes two infertile patients who experienced significant improvements in sperm concentrations six months after stopping finasteride.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

This study found that disrupting testosterone biosynthesis in male rats mitigated cardiovascular and autonomic impairments caused by endotoxemia, indicating testosterone's significant role in these conditions.

Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.

This review explores the mechanisms of intratesticular control of steroidogenesis and indicates the need for further controlled studies; it presents no new experimental findings.

This study reported that postnatal environmental factors, such as childhood height and early hospitalization for immune-related diseases, were associated with an increased risk of testicular germ-cell tumor, with minimal observed variation between seminomas and non-seminomas.

Men with early balding may have a higher risk of prostate issues, and surgery for prostate cancer has a slight survival benefit over radiation.

In this study, dutasteride more effectively reduced prostate cancer cell viability than finasteride in vitro, but did not significantly alter the angiogenic response.

This study is the first to detail major geriatric diseases in aged Julia Creek dunnarts, particularly highlighting hormonal issues like cystic glandular hyperplasia in females and testicular degeneration in males, suggesting these conditions are linked to aging and potentially hormonal dysregulation.

In this animal study, finasteride was found to significantly lower cortisol and increase testosterone levels in female rats, indicating its broader impact on endocrine regulation by altering adrenal and gonadal hormones.

This case report describes a Canadian Husky dog with sertolioma that exhibited dermatological symptoms and aggressive behavior, both of which improved significantly after surgery.

In this study of BPH patients with testosterone deficiency, the combination of TU and dutasteride reduced prostate volume and improved testosterone-related symptoms but was less effective for sexual function compared to TU alone, indicating caution in using dutasteride for those with sexual dysfunction concerns.

This study found that male pattern baldness may serve as a clinical marker for circulating sex hormone levels in men with localized prostate cancer, while chest hair density showed no significant hormone association.

This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.

This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.

This study identified that derivatives 4, 4b, and 4c strongly inhibited the enzyme type 1 5α-reductase and decreased reproductive organ weights in hamsters, suggesting potential as prodrugs for prostate tumor growth inhibition.