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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

The therapies improved ejaculation disorders and sexual function in middle-aged men.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

New genes and pathways are important for testosterone production and male sexual development.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Finasteride has a higher risk of reproductive side effects than minoxidil.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Plum blossom needle acupuncture with qi-invigorating therapy is more effective for Seborrheic Alopecia than Western medicine.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Medications for hair loss and prostate issues can significantly increase the risk of sexual side effects and other negative symptoms.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The document does not determine if adults with aphallia are fertile.

Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.