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Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

About 15% of US Army personnel use hair products containing hormone or placenta, with higher usage among non-whites, females, and enlisted personnel.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Accurate assessment of puberty using Tanner staging is crucial for identifying normal and abnormal development.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

Testosterone is vital for male health, and its deficiency is linked to aging and common health issues.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

More research is needed to understand how testosterone is maintained in adult males.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The painting of an 18th-century Sicilian baroness shows she had hair loss, possibly due to ovarian issues, insulin resistance, or a specific type of tumor.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.