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Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

High testosterone increases heart disease risk in women with PCOS.

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Hyperthyroidism can hide signs of high androgen levels in females.

PCOS may have evolved as an advantage in past environments with food scarcity.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The Rotterdam Study aims to understand various diseases in older adults.

Androgens can both increase and decrease hair growth in different parts of the body.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.