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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Lower SHBG levels may increase the risk of PCOS.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Lentiginous melanoma is most common on the face, especially the nose, cheek, and pre-auricular areas, with men more likely to have it on the scalp, ears, upper back, and trapezius, and women on the cheek and anterior arm. Sun damage is a key factor in its formation.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Patients with rheumatoid arthritis using tofacitinib had more serious side effects than those with alopecia areata.

The critique suggests that Wilton's work unintentionally supports the very stereotypes it aims to question and calls for a broader, more inclusive approach to understanding gender.

Older men and those with a history of skin cancer have a higher risk of getting skin cancer again.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Men's hair loss is not linked to their sex hormone levels, except for lower DHEAS in those with hair loss.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

Regulating certain sex hormones may help delay facial aging.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Neutered ferrets often develop hyperadrenocorticism, with symptoms like hair loss and lethargy, and androstenedione is a key indicator for diagnosis.

More research is needed to understand sex and racial differences in long COVID.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Methotrexate side effects vary by race and sex.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Men have more tryptophan in their hair than women, and it increases with age and is higher in darker and grey or white hair.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Men and women react differently to opioids, with hormones potentially influencing these differences.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Omega-6 fats in certain cells boost male hormone production.