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Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.

A Brazilian teenager with severe hair loss had total hair regrowth with no side effects after using tofacitinib.

Adolescents with severe alopecia incur significantly higher healthcare costs.

People with severe hair loss (Alopecia Areata) have different scalp bacteria than healthy people, which might help predict the condition's progress.

Azathioprine may help treat severe alopecia areata, but more research is needed.

New treatments for severe alopecia areata, especially JAK inhibitors, are recommended as first-line therapy.

Adults and adolescents with severe alopecia areata are willing to take significant health risks for a better chance of hair regrowth.

Patients with severe alopecia areata felt better and less anxious or depressed when treated with baricitinib compared to placebo.

People with severe alopecia areata often have lower vitamin D levels and may have other autoimmune or allergic conditions.

People with severe Alopecia Areata have higher levels of TGF-β1, which may play a role in the condition.

The study found that severe alopecia areata affects any age, treatments often give temporary results, and some factors predict worse outcomes.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Leflunomide and anthralin may effectively treat severe alopecia areata.

Tofacitinib is effective and safe for treating severe hair loss in a Saudi population.

Current corticosteroid pulse therapy is not very effective for severe rapidly progressive alopecia areata.

JAK inhibitors offer new hope for treating severe alopecia areata.

Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

Intramuscular corticosteroids are effective and safe for severe alopecia areata, with most patients regrowing hair, but nearly half may relapse.

Tofacitinib is a promising treatment for severe alopecia areata, with many patients experiencing complete or partial hair regrowth.

More effective treatments are needed for severe alopecia areata.

Baricitinib is a promising treatment for severe alopecia areata with minimal side effects.

JAK inhibitors like tofacitinib can effectively treat severe alopecia areata.

Low vitamin D levels are linked to severe and active alopecia areata.

Higher IL-17A levels indicate more severe alopecia areata.

IMTA can help regrow hair in severe alopecia areata when JAK inhibitors don't work well.

Tofacitinib shows promise for treating severe alopecia areata with good safety and effectiveness.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Older age at onset of alopecia areata leads to less severe and shorter episodes, with most patients experiencing significant hair regrowth.