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The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

Treatments for hair loss vary, but cell-based options may be the future.

No significant difference in iron deficiency between women with or without hair loss.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Finasteride with oral contraceptive helps improve hair loss in premenopausal women.

Lowering testosterone speeds up wound healing in male mice.

Lower SHBG levels may increase the risk of PCOS.

FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

FFA's causes may include environmental triggers and genetic factors.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.