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Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Androgens can help prevent memory problems caused by apoE4.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Myrtle has various health benefits and potential for medicine development.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.