Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, dose-response modeling predicted that once-daily abrocitinib doses of 100 mg and 200 mg may provide a clinically meaningful response in treating moderate-to-severe atopic dermatitis compared to placebo.

This study found that a history of smoking significantly predicted a more refractory course of palmoplantar pustulosis, with associated comorbidities often including hypertension, type 2 diabetes mellitus, and thyroid diseases.

This study observed that different roles in dermatology clinics have varying levels of understanding and awareness of the overall clinic visit process, with educational interventions potentially enhancing clinic efficiency and quality of care.

This article discusses hair and nail research contributions in dermatology but reports no new clinical findings.

This study found that finasteride treatment reduced urinary androgen and prostaglandin levels in male pattern baldness patients to levels similar to healthy controls.

This study suggests that androgen receptor gene CAG repeat length may influence serum free testosterone levels in some PCOS patients, with longer repeats associated with higher testosterone concentrations.

This study found no strong evidence that the human hairless gene is significantly involved in the development of androgenetic alopecia, though a minor role cannot be completely ruled out.

This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.

This study identifies six novel keratin genes from the chromosome 17q21.2 region, suggesting their association with hair follicles, while all 27 keratin genes in the domain have been characterized transcriptionally.

In this study, researchers developed a non-invasive method to distinguish exogen hair from telogen hair on the human scalp, finding that normal exogen hair levels are generally less than seven hairs per cm².

In this study, researchers observed that African spiny mice, Acomys cahirinus, are capable of regenerating skeletal muscle in dermal wound sites, unlike common mice, Mus musculus.

In this study, a combination of spironolactone and finasteride was found to significantly improve hirsutism scores without increasing side effects compared to spironolactone alone.

This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.

Certain treatments can speed up local hair growth in mice but don't change the overall hair growth pattern.

In this study, researchers identified key mRNA and microRNA regulatory mechanisms that influence cashmere growth in cashmere goats under different photoperiods, potentially offering new methods to enhance cashmere production.

This study suggests that seasonal rhythm genes in cashmere goat skin are differentially expressed with changing daylight, potentially affecting hormone transformation and light sensitivity.

This study found that systemic lupus erythematosus was diagnosed earlier in males than females, with a notable delay in diagnosis for females often due to confounding symptom overlaps with other conditions.

Some human genetic markers work for genetic studies in pig-tailed and stump-tailed macaques, which can help in their conservation.

This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.

This study found that keratin-associated proteins related to metallothionein and occludin appear in various animals, suggesting they may have roles beyond hair characteristics and were later adapted for hair production.

This study concluded that STK11 gene polymorphisms were not predictive of metformin response in women with PCOS, though they may influence alopecia and hirsutism.

This study found that mutant glucocorticoid receptors have defective transcriptional activity and dynamic motility issues in the nucleus, likely due to impaired interactions with nuclear molecules necessary for gene activation.

This review discusses the implications of deterministic chaos in pathology, emphasizing its potential impact on predicting biological behavior of lesions, and reports no new experimental results.

This review explores the current understanding of genetic and hormonal influences on male androgenetic alopecia and female pattern hair loss, providing guidance for clinicians but reports no new results.

This study found that among Japanese IBD patients, the NUDT15 p.Arg139Cys variant was significantly associated with thiopurine-induced leukopenia and severe hair loss, suggesting its genotyping is important for predicting these adverse events.

This review discusses the potential regulation of signal transduction pathways by microRNAs in animal cells, aiming to identify biological processes that may be influenced by miRNA-mediated regulation, but it reports no new experimental outcomes.

This review explores recent advances in understanding molecular mechanisms of tissue regeneration in mammals and suggests potential therapeutic targets, but it reports no new clinical results.

This review discusses evidence on androgen sensitivity as a potential factor in COVID-19 disease severity, suggesting that androgen receptor interactions could influence virus entry and progression, and reports no new clinical results.

This review discusses the hair follicle cycle's complex regulation and highlights the potential for targeting catagen control in future therapies without presenting new experimental data.