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Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Critical illness can lead to long-lasting physical and psychological problems, requiring ongoing, specialized care and rehabilitation.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

A woman with lupus and severe nerve damage improved with specific treatments.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

A patient developed nerve problems as a side effect of a hair loss treatment called tofacitinib.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.