165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
156 citations,
December 2012 in “Cell Stem Cell” TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
143 citations,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
132 citations,
August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
126 citations,
April 2010 in “Seminars in Cancer Biology” Deregulation of stem cell function is central to the development of some cancers.
96 citations,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
86 citations,
May 2011 in “Journal of The American Academy of Dermatology” How bad a woman's hair loss is doesn't always match how it affects her happiness and daily life.
75 citations,
June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
68 citations,
March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
58 citations,
November 2020 in “International Journal of Dermatology” COVID-19 may cause a temporary hair loss condition called telogen effluvium in some patients after recovery.
57 citations,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
51 citations,
March 2001 in “Clinics in dermatology” Bleaching damages hair, making it rougher and weaker.
50 citations,
January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
48 citations,
July 2002 in “Journal of Cutaneous Medicine and Surgery” Skin problems are common and important signs of eating disorders and treating the eating disorder can improve these skin conditions.
45 citations,
November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
38 citations,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
36 citations,
October 2014 in “Langmuir” Bleaching hair removes its protective top layer and exposes more hydrophilic groups, changing its chemical surface and affecting how it interacts with products.
35 citations,
July 2008 in “Dermatologic therapy” Cicatricial alopecia may be caused by immune attacks on hair follicles, gland issues, or stem cell damage.
32 citations,
October 1999 in “Journal of women's health and gender-based medicine” Hair loss greatly affects women's mental health and appearance satisfaction.
31 citations,
November 2000 in “Clinical and Experimental Dermatology” WAA-QOL measures impact of hair loss on women's well-being.
31 citations,
November 2000 in “Journal of the European Academy of Dermatology and Venereology” Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.
30 citations,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
27 citations,
March 2013 in “Social Semiotics” Commercial hair loss websites promote Propecia by making men feel insecure about baldness and suggesting it's a medical issue needing treatment.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
24 citations,
January 2017 in “Journal of Cutaneous and Aesthetic Surgery” Botulinum toxin was found to be a safe and effective treatment for male pattern baldness in a small test, but more research is needed.
22 citations,
December 2013 in “Stem cells and development” Horse skin stem cells combined with platelet-rich plasma improve skin healing.
21 citations,
November 2015 in “Phytomedicine” Glycyrrhizic acid may help reduce unwanted hair growth.
21 citations,
January 1988 in “Stress Medicine” Stress affects skin health and emotional well-being should be considered in skin disease treatment.