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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Targeting hair follicles can improve skin treatments and reduce side effects.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Vitamin D3 affects cell differentiation in specific skin areas.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

Melatonin may reduce skin damage caused by X-rays in rats.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

RU 58841 may treat acne, hair loss, and excessive hair growth.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.