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Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.

People with Down's syndrome often have more skin problems due to a weak immune system.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

MRI can effectively image skin structures noninvasively.

People with Lichen planopilaris are more likely to have certain autoimmune and endocrine disorders but less likely to have conditions like allergies and diabetes.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Early hair whitening may indicate a higher risk of heart disease in young and middle-aged men.

The document concludes that there are no reliable treatments for frontal fibrosing alopecia, with only temporary benefits from current options.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.

Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.

Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.