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      Pityrosporum Species as a Cause of Allergy and Infection

      research Pityrosporum species as a cause of allergy and infection

      89 citations , May 1999 in “Allergy”
      This article reviews the role of Pityrosporum (Malassezia) in skin conditions such as pityriasis versicolor, seborrheic dermatitis, and atopic dermatitis, and discusses treatment approaches; it reports no new clinical results.
      The Pathogenesis of Alopecia Areata

      research THE PATHOGENESIS OF ALOPECIA AREATA

      89 citations , October 1996 in “Dermatologic Clinics”
      This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.
      No Evidence for the Immunocompetence Handicap Hypothesis in Male Humans

      research No evidence for the immunocompetence handicap hypothesis in male humans

      87 citations , May 2018 in “Scientific Reports”
      This study found that in healthy men, higher levels of free testosterone were associated with a stronger immune response to the influenza vaccine, suggesting androgens may function as immunomodulators rather than strict immunosuppressants.
      Hair Shafts in Trichoscopy

      research Hair Shafts in Trichoscopy

      86 citations , October 2013 in “Dermatologic Clinics”
      Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.
      Nanozymes Expanding the Boundaries of Biocatalysis

      research Nanozymes expanding the boundaries of biocatalysis

      85 citations , July 2025 in “Nature Communications”
      This review examines the evolving field of nanozymes, highlighting their unique properties and biocatalytic capabilities that challenge traditional concepts of biocatalysis, with implications for sustainable applications and potential roles in physiological processes and disease pathogenesis.
      Alopecia Areata Update

      research Alopecia Areata Update

      85 citations , October 2012 in “Dermatologic Clinics”
      This article reviews recent updates on alopecia areata, focusing on its causes, clinical presentation, and treatment options, and provides treatment plans by patient age and disease extent, but reports no new clinical results.
      Hair Analysis in Health Assessment

      research Hair analysis in health assessment

      84 citations , February 2013 in “Clinica chimica acta”
      This review presents evidence that correlations exist between hair mineral imbalances and various diseases, though inconsistencies in results highlight the need for standardized preparation methods.
      Human αβ and γδ T Cells in Skin Immunity and Disease

      research Human αβ and γδ T Cells in Skin Immunity and Disease

      83 citations , June 2018 in “Frontiers in immunology”
      This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
      Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

      research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

      81 citations , November 2012 in “Journal of the National Cancer Institute”
      This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.
      Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification

      research Inherited ichthyoses/generalized Mendelian disorders of cornification

      81 citations , June 2012 in “European journal of human genetics”
      This review outlines a diagnostic framework for clinicians to distinguish different types of inherited ichthyoses and suggests further testing and treatment strategies, but reports no new clinical results.
      Eating Disorders: Progress and Challenges

      research Eating Disorders: Progress and Challenges

      81 citations , January 2011 in “European Journal of Internal Medicine”
      This review updates on the understanding and management of eating disorders, noting substantial progress over 30 years but highlighting the need for revised classification, clarified pathogenesis, and improved treatments.
      Pharmacological Activity and Clinical Use of Polydeoxyribonucleotide

      research Pharmacological Activity and Clinical Use of PDRN

      80 citations , April 2017 in “Frontiers in Pharmacology”
      This review examines experimental and clinical evidence on PDRN, a drug derived from salmon DNA that acts via the adenosine A2A receptor and shows promise for tissue repair and treatment of diabetic foot ulcers in regenerative medicine.
      Elastic Tissue in Scars and Alopecia

      research Elastic tissue in scars and alopecia

      80 citations , March 2000 in “Journal of cutaneous pathology”
      This study found that the Verhoeff-Van Gieson stain effectively distinguishes scarred from non-scarred dermis and aids in classifying types of permanent alopecia based on elastic tissue patterns.
      Skin Connective Tissue and Aging

      research Skin connective tissue and ageing

      77 citations , July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.
      Methotrexate in Dermatology

      research Methotrexate in dermatology

      77 citations , July 2007 in “Dermatologic Therapy”
      This review discusses methotrexate's use in dermatology and its mechanisms, pharmacokinetics, dosing, side effects, interactions, and emphasizes the need for further research into optimizing therapy and predicting adverse events.
      Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

      research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

      76 citations , February 2021 in “International Journal of Molecular Sciences”
      This review examines how mesenchymal stem cells and their derivatives may enhance skin regeneration and rejuvenation, but it reports no new clinical results; the authors suggest iPSC-derived MSCs hold promise for future therapies.
      Stem Cells in Tissues, Organoids, and Cancers

      research Stem cells in tissues, organoids, and cancers

      76 citations , July 2019 in “Cellular and Molecular Life Sciences”
      This article reviews the role of stem cells in tissue development, tumor formation, and organoid generation, and highlights the potential of epigenetic regulation in advancing regenerative medicine and cancer treatment, without presenting new experimental results.
      Alopecia: Evaluation and Treatment

      research Alopecia: evaluation and treatment

      76 citations , July 2011 in “Clinical, Cosmetic and Investigational Dermatology”
      This review discusses clinical methods for diagnosing alopecia and examines current treatments for both cicatricial and noncicatricial forms but provides no new clinical results.
      A Histologic Review of 27 Patients with Lichen Planopilaris

      research A histologic review of 27 patients with lichen planopilaris

      76 citations , June 2008 in “Journal of the American Academy of Dermatology”
      In this study, key histologic features such as mucinous perifollicular fibroplasia were identified to aid in the diagnosis of lichen planopilaris.
      Mushroom Cosmetics: The Present and Future

      research Mushroom Cosmetics: The Present and Future

      73 citations , July 2016 in “Cosmetics”
      This review discusses the use of mushrooms and their bioactive compounds in cosmeceuticals and nutricosmetics and reports no new clinical findings, highlighting potential areas for future research and development.
      Ethnic Hair Update: Past and Present

      research Ethnic hair update: Past and present

      73 citations , June 2003 in “Journal of the American Academy of Dermatology”
      This article reviews common hair-care practices among African American patients and discusses how these practices relate to hair and scalp disorders, without presenting new clinical research.