Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified four genes related to alopecia areata: GIMAP6 and ALOX15 as risk factors, and GALNT6 and HEG1 as protective factors, noting significant validation differences in GALNT6 and HEG1.

This study found that hair testosterone concentrations show some consistency over time, but factors like hair washing and individual growth rates influence these levels, suggesting the need for careful sampling and analysis adjustments.

Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.

This article reviews the proposed mechanism of minoxidil in treating androgenetic alopecia, suggesting it may prolong the anagen phase by modulating cell growth factors and vascular activity, but reports no new results.

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

In this study, the researchers established a dose–response relationship between the hair follicle dose during cranial irradiation and the development of permanent alopecia, with other factors showing limited correlation.

This study found that sebum excretion is not increased in women with female pattern hair loss, suggesting nonandrogenic factors may contribute to hair loss in some women without hirsutism.

This review suggests that paradoxical hair growth after light-based treatments is unlikely due to the devices themselves; instead, it may be linked to other factors such as inflammation in individuals with certain conditions.

This study reported that AutoML effectively modeled itching and pain development, as well as app use, in patients with chronic eczema or psoriasis using a smartphone monitoring app, revealing that factors like BMI, age, and disease activity significantly influenced app engagement.

This study found that Tinea Corporis significantly impacts the quality of life of patients, with disease duration and body surface area involved being key factors.

In this cross-sectional study of healthy urban women in Shanghai, poor sleep quality and elevated perceived stress were linked to various self-reported dermatological issues and clinical signs, reinforcing the potential relevance of psychological factors in skin health.

In this prospective cohort, baseline severity, disease activity, and relapse history were identified as key factors influencing response and recurrence in alopecia areata, suggesting that implementing standardized assessments could enhance risk stratification and personalized care approaches.

This study observed that testosterone concentrations in hair segments show some stability over time, but are influenced by factors like sebum integration, hair washing frequency, and individual hair growth rates.

This study found that glycated proteins in untreated scalp hair may serve as a non-invasive marker for blood glucose control, but its applicability is limited by factors like cosmetic treatments and sample collection challenges.

This study reports that despite rescuing neurulation and skin barrier defects, Grhl3 gene overexpression in mice leads to hearing impairment, hair loss, and other developmental abnormalities, highlighting low tolerance for Grhl3 dysregulation.

In this study, scalp hair sweating was a significant predictor of hair cortisol levels in healthy adults, while BMI and perceived stress, although associated, did not significantly predict cortisol levels.

This study identified the transcription factor Elf5 as a novel regulator of keratinocyte proliferation and differentiation in skin, with expression elevated in stem/progenitor cell populations, suggesting its potential role in determining cell fate during skin and hair development.

This study found that deleting Snai2 and Snai3 genes in mice disrupts immune cell development, resulting in severe autoimmunity and early death due to the loss of immune tolerance.

This study discovered that the gene Tfap2b identifies a melanocyte stem cell population in zebrafish, essential for regenerating melanocytes with multi-fate potential into adult pigment cells.

This study suggests that TGF-β 2 plays a critical role in hair follicle morphogenesis and may enhance the effectiveness of future cell therapies for hair regrowth using expanded dermal papilla cells.

This study found that TAp63 and ΔNp63 isoforms in the p63 family interact with different transcription factors to regulate distinct transcriptional programs, affecting various biological functions like metabolic pathways, oxidative stress response, and epithelial morphogenesis in mouse epidermal cells.

This review found that while forensic DNA phenotyping and health applications for pigmentation genetics show potential, factors like phenotype definition and population diversity present challenges to accurate genotype-to-appearance predictions.

This study explored Ayurvedic treatments for Khalitya (Alopecia areata) and found that using Virechana Karma, along with systemic medicines and Rasayan drugs, may be extremely beneficial in managing this condition.

This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.

This study found that arachidonic acid may promote hair growth by enhancing dermal papilla cell function and stimulating the anagen phase in C57BL/6 mice.

Hair loss caused by genetics and hormones; more research needed for treatments.

This study suggests that skin sections from 4-week-old C3H mice could serve as an in vitro model for human androgenic alopecia, as minoxidil partially reverses suppressed hair follicle elongation.

This study found that adapalene-loaded microemulsions significantly enhanced the drug's penetration through guinea pig skin compared to an aqueous suspension, with factors like surfactant ratios and the water-oil phase balance affecting the transfollicular drug delivery efficiency.

This study found that patients with alopecia areata exhibited increased CRHR1 expression on circulating monocytes compared to controls, suggesting that stress-related factors like CRH and CRHR1 may contribute to the development and progression of the condition, particularly in chronic cases and those with larger lesions.

This study reports that Elvitegravir, a drug currently approved for other uses, shows potential as a neuro- and mitoprotective agent by attenuating mitochondrial damage caused by NMDA receptors in primary mouse cortical neurons.