September 2023 in “Gynäkologische Endokrinologie” This review discusses how the hormonal changes of menopause affect skin and hair, highlighting improvements in skin symptoms like dryness and reduced wound healing with estrogen supplementation, and advises healthcare providers to consider broader potential benefits of menopausal hormone therapy when consulting patients.
66 citations
,
October 2006 in “Journal of Surgical Oncology” This review discusses current techniques for scalp reconstruction following oncologic surgery and reports no new clinical outcomes, emphasizing the importance of tailored approaches for satisfactory closure.
14 citations
,
September 2001 in “Dermatologic Surgery” This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.
8 citations
,
December 1996 in “Dermatologic Surgery” This article discusses surgical innovations in scalp reduction to improve cosmetic outcomes but reports no new clinical results, emphasizing the benefits of anchor techniques for minimizing scars and stretch-back.
January 2026 in “International Society of Hair Restoration Surgery” In this case study, a 35-year-old male with severe burn-related scalp injuries underwent successful reconstruction through tissue expansion, skin grafts, and multiple hair transplant sessions, resulting in satisfactory aesthetic and functional recovery.
January 2007 in “Dermatologic Surgery” This study presents a new surgical technique that frequently results in minimal scars visible to the naked eye, marking a significant improvement over traditional methods.
September 2001 in “Dermatologic Surgery” This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.
16 citations
,
July 2006 in “International Journal of Oral and Maxillofacial Surgery” This case report highlights the successful use of the Bardach modification of the curved tripod flap for repairing cicatricial pressure alopecia, offering a natural appearance and effective tension distribution in scalp reconstruction.
16 citations
,
October 1979 in “The Journal of Dermatologic Surgery and Oncology” In this report, a 17-year-old boy received successful scalp reduction surgery for alopecia due to a thermal burn, achieving excellent cosmetic results without hypertrophic or keloidal scarring.
12 citations
,
September 2020 in “Stem cell research & therapy” This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.
6 citations
,
July 2021 in “Microbial biotechnology” This study found that combining LED yellow light with an engineered strain expressing CXCL12 improved wound healing and reduced inflammation in a mouse model of scald wounds.
4 citations
,
January 2000 in “Durham e-Theses (Durham University)” This study found that anagen skin in PVG rats showed significantly smaller wound diameters compared to telogen skin at 7 and 8 days after wounding, suggesting the importance of hair follicle dermal components in wound healing.
3 citations
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January 1988 in “PubMed” This study found that scalp basal cell carcinomas do not appear to behave more aggressively than other types, despite suggestions in the literature.
1 citations
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January 2025 in “Head & Neck” In this report, researchers highlighted the snail flap as a highly reliable and minimally invasive reconstructive technique that preserves hair and requires minimal hospitalization, making it suitable for elderly or frail patients with moderate scalp defects.
July 2026 in “International Journal for Research in Applied Science and Engineering Technology” This study explored the use of Kasisadi Lepa, a classical herbo-mineral formulation, and found its components could reduce dandruff by addressing scalp inflammation, microbial growth, and tissue damage with potential integration into long-term scalp health strategies.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This narrative review from the authors discusses mechanical scalp stimulation as a potential treatment for androgenetic alopecia, suggesting it has a biologically plausible mechanism but immature clinical evidence; marketing of these devices currently outpaces their supporting data, indicating a need for better-controlled trials.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This narrative review suggests that while mechanical scalp stimulation has a plausible mechanism for aiding androgenetic alopecia, its clinical evidence is insufficient, and the marketing of stimulation devices currently outpaces their efficacy data.
July 2025 in “Cosmoderma” This review discusses the various applications of platelet-rich plasma in dermatology, particularly its potential in esthetic dermatology and hair and scalp conditions, but reports no new clinical findings.
December 2023 in “Curēus” In this case study, researchers reported the first instance of keratoacanthoma on the scalp of an elderly patient in Saudi Arabia, highlighting the diagnostic challenge due to its resemblance to squamous cell carcinoma.
47 citations
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October 2021 in “Journal of Nanobiotechnology” This study found that hollow polydopamine nanoparticles enhanced the regenerative potency of the peptide RL-QN15, suggesting potential for improved therapeutic approaches in skin wound healing.
August 2023 in “Molecules and Cells” In this review, researchers explored how various cell types and molecular mechanisms contribute to wound-induced hair follicle neogenesis, highlighting its potential as a therapeutic approach for regenerating hair follicles and minimizing scar formation after injury.
25 citations
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December 2021 in “Stem Cell Research & Therapy” This review discusses the potential of mesenchymal stem/stromal cells and their exosomes in promoting wound healing and skin regeneration, but reports no new experimental results.
This review highlights the cosmeceutical potential of tropical herbs due to their bioactive compounds like flavonoids and saponins, which offer antioxidant and anti-inflammatory benefits, though it notes challenges such as lack of standardized formulations and large-scale validation in current research.
June 2025 in “Advances in Clinical and Experimental Medicine” This study highlights keratin biomaterials as a promising biocompatible option for wound healing and tissue regeneration but notes that further clinical studies are necessary to confirm their effectiveness.
April 2024 in “Vestnik dermatologii i venerologii” This review highlights the diagnostic potential and therapeutic prospects of exosomes, discussing their use in managing chronic immune-mediated skin conditions, alopecia, and wound healing through their capacity to deliver regulatory molecules between cells.
August 2023 in “Skin Research and Technology” This study found that platelet-rich plasma is effective and safe for treating chronic wounds, particularly diabetic and venous ulcers, and vitiligo, without increasing the risk of infection.
20 citations
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February 1991 in “The Journal of Dermatologic Surgery and Oncology” This article discusses scalp reconstruction techniques using rotation flaps, with no new clinical results reported.
16 citations
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March 2025 in “International Journal of Molecular Sciences” This review analyzed 12 clinical studies on extracellular vesicle therapies, finding potential benefits for skin aging, acne scars, alopecia, and wound healing, but highlighted significant challenges like production standardization and lack of large-scale studies.
37 citations
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December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
21 citations
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December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that fibroblast behavior switching between proliferation and ECM deposition is vital for dermal architecture, where cell migration is primarily important for tissue repair during wound healing.