July 2026 in “Frontiers in Cellular and Infection Microbiology” This study found that patients with androgenetic alopecia had increased scalp microbial diversity and reduced Staphylococcus abundance, particularly in the frontal and vertex regions, suggesting this dysbiosis as a sensitive indicator of AGA.
June 2026 in “Pathology & Oncology Research” In this study, the Orbis PAXMAN® scalp cooling system showed effectiveness and good tolerability in preventing chemotherapy-induced hair loss in breast cancer patients, particularly those receiving anthracycline-free chemotherapy, though the presence of comorbidities was linked to a higher risk of severe alopecia.
December 2025 in “Aesthetic Cosmetology and Medicine” This study reported that platelet-rich fibrin (iPRF) therapy may improve scalp health and hair appearance in women, showing beneficial changes in scalp hydration, redness, oiliness, and hair density, thickness, and loss.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this review, researchers examined the concentration of cortisol in scalp hair of individuals with alopecia areata to explore its relationship with disease variables, as cortisol in hair can indicate chronic stress, which may impact alopecia areata pathogenesis.
February 2025 in “Plastic and Aesthetic Research” In this study, after long-term observation of human scalp hair follicles over 16 years, the researchers found that a topical 5% minoxidil solution could stimulate hair regrowth after a period of dormancy, though with reduced growth rates and hair diameter.
June 2024 in “Nature Cell and Science” In this research, experienced clinicians noted inconsistency in the reproducibility of the commonly used Hamilton-Ludwig scales for assessing pattern hair loss severity in photographic assessments, leading to the proposal of a new 5-point scale for staging female hair loss.
May 2007 in “Dermatologic Therapy” Hair care practices like using relaxers and tight braiding can lead to permanent hair loss in black women.
227 citations
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January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.
69 citations
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January 2015 in “Current problems in dermatology” This review discusses trichoscopy as a noninvasive, effective technique for diagnosing various hair loss conditions and monitoring treatment, highlighting its potential to reduce scalp biopsy necessity.
37 citations
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May 1999 in “Australasian Journal of Dermatology” This review discusses neutrophil-associated and infiltrative scarring alopecias, as well as promising new treatments, but reports no new clinical results.
29 citations
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September 1989 in “Journal of The American Academy of Dermatology” This article describes cases of unusual scalp whorl patterns, including triple parietal and right temporal whorls, that were associated with normal development, and discusses theories of hair whorl development.
28 citations
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November 2017 in “Skin appendage disorders” This paper proposes a systematic approach to evaluating scalp itch using the SCALLP acronym and highlights the importance of classifying cases based on the presence of dermatological lesions and hair loss, but it reports no new clinical findings.
28 citations
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January 2007 in “Journal of dermatology” This case report describes instances of lipedematous scalp and lipedematous alopecia in white adults, indicating these rare conditions may be more widespread and frequent in this population than previously thought.
26 citations
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January 2014 in “Annals of Dermatology” This report describes a 33-year-old woman who developed alopecia neoplastica due to gastric adenocarcinoma, highlighting the role of tumor invasion in hair follicle atrophy.
19 citations
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September 2011 in “Clinical and Experimental Dermatology” This study suggests that for single biopsy specimens, transverse sections may be preferable for diagnosing noncicatricial alopecia, while vertical sections may be better for suspected lichen planopilaris.
16 citations
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October 2012 in “British Journal of Dermatology” Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.
14 citations
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June 2019 in “BMC infectious diseases” This study presents the first reported case of kerion-type scalp mycosis caused by Aspergillus protuberus, emphasizing the importance of mycological examination when diagnosing unusual scalp infections, especially in children.
6 citations
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January 2015 in “Dermatology” This review covers trichoscopy's role in diagnosing scalp disorders, emphasizing its potential to improve clinical accuracy, but it reports no new clinical results.
5 citations
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March 2017 in “Laser Physics Letters” This review discusses the role of scalp imaging techniques in trichology for researching drug delivery and toxicology, without presenting new clinical results.
3 citations
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February 2016 in “Pediatric dermatology” This report describes two cases of Rapp–Hodgkin ectodermal dysplasia where refractory scalp erosions improved significantly with potent topical steroids; it also suggests a potential link between these scalp conditions and erosive pustular dermatosis of the scalp in elderly patients.
2 citations
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January 2023 in “Annals of Dermatology” A hairless patch on a boy's scalp from birth injury improved with minoxidil treatment.
April 2026 in “International Journal of Drug Delivery Technology” This study found trichoscopy to be a reliable non-invasive method for diagnosing various forms of alopecia, aiding in clinical management and reducing the need for biopsies in a hospital-based setting with 90 patients, including those with uncertain diagnoses.
September 2025 in “Sahel Journal of Life Sciences FUDMA” This study reported that albino Wistar rats exposed to chemical hair straighteners showed significant hair fiber damage and scalp skin deterioration, which worsened with repeated and prolonged application, highlighting the cytotoxic potential of these products and potential systemic risks.
September 2025 in “Acta Scientific Pharmaceutical Sciences” This paper examines the rising popularity and potential benefits of rice water for hair care, noting that while it contains beneficial compounds like inositol that may increase hair strength and decrease frizz, there is still no definitive scientific proof of its efficacy.
February 2024 in “International Journal of Research in Dermatology” In this study, researchers examined thyroid function and autoantibody levels in patients with alopecia areata and vitiligo, finding similar rates of thyroid dysfunction and autoantibody presence in both groups, with no significant differences based on ethnicity or gender.
September 2023 in “Clinical, cosmetic and investigational dermatology” In this study, the researchers found that a 28-day topical treatment with a postbiotic ferment complex notably altered the scalp microbiome in women with sensitive scalps, increasing certain bacterial species and decreasing others, while also reportedly alleviating symptoms of sensitive skin syndrome in all participants.
This case study reports an unusual presentation of erosive lichen planus of the scalp linked to hepatitis C in a patient, highlighting challenges in establishing a definitive correlation between the two conditions.
308 citations
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December 2018 in “PLOS Genetics” This study identified three novel genetic loci associated with PCOS and found similar genetic architecture across different diagnostic criteria, with evidence suggesting genetic links between PCOS and various metabolic and psychological traits.
77 citations
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June 2007 in “PLoS ONE” This study identified changes in transcription factor gene expression across various signaling pathways during inner ear hair cell regeneration in birds, revealing patterns and potential new pathways for future investigation.
10 citations
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November 2017 in “Journal of Investigative Dermatology” In this study, researchers identified a novel homozygous variant in the FAM83G gene responsible for autosomal recessively inherited palmoplantar keratoderma with curly hair in a consanguineous Pakistani family, suggesting FAM83G plays a crucial role in skin and hair homeostasis.