16 citations,
January 2010 in “Drug Metabolism and Pharmacokinetics” Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
16 citations,
August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
15 citations,
January 2019 in “Journal of the Formosan Medical Association” Adalimumab helped control a child's severe eye disease when other treatments failed.
13 citations,
May 2016 in “International journal of biological macromolecules” Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
13 citations,
November 2005 in “Veterinary Dermatology” A dog's skin calcification condition resolved without treatment after a bacterial infection.
12 citations,
July 2019 in “Acta Neurologica Belgica” Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.
12 citations,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Methotrexate's effectiveness for maintaining hair regrowth in alopecia totalis is unclear due to limited and biased data.
12 citations,
December 2013 in “The Journal of Urology” Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.
12 citations,
April 2008 in “Indian Journal of Dermatology” There's no significant relationship between hair loss (androgenetic alopecia) and demodex infestation.
12 citations,
March 2004 in “International Journal of Dermatology” Woman's hair loss diagnosis changed from CTE to AA; multiple biopsies important for accurate diagnosis.
12 citations,
January 1978 in “The Laryngoscope” Using a scalp flap for hair transplantation gives denser, faster results than older methods, but it's complex and needs careful planning.
11 citations,
March 2021 in “Dermatology and therapy” Researchers created a new tool to measure the effects of alopecia areata from the patient's view, focusing on hair loss, daily life, and emotional health.
11 citations,
June 2017 in “Journal of cell science” AGD1's PH domain is essential for its role in root hair growth and polarity.
11 citations,
November 2015 in “Skin Research and Technology” Women's hair grows faster and thicker than men's, but hair growth slows for both genders with pattern hair loss.
11 citations,
August 2011 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
10 citations,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
10 citations,
September 2020 in “Biopolymers” Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.
10 citations,
March 2016 in “Journal of The American Academy of Dermatology” Finasteride's effectiveness for frontal fibrosing alopecia is uncertain.
10 citations,
February 2015 in “Journal of Pharmaceutical and Biomedical Analysis” Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
10 citations,
May 2013 in “Actas Dermo-Sifiliográficas” Most white Spanish women have a widow's peak, and their hairline measurements could help in hair restoration surgery.
10 citations,
January 2013 in “International journal of trichology” A woman's scalp nodules were successfully treated with antifungal and anti-lice medications, revealing a rare case of mixed piedra infection.
10 citations,
July 2001 in “Hair transplant forum international” The document's conclusion cannot be provided because the document is not readable or understandable.
9 citations,
April 2019 in “Journal of structural biology” Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
9 citations,
March 2018 in “Actas Dermo-Sifiliográficas” The Spanish version of the Hair Specific Skindex-29 scale is a reliable and valid way to measure the impact of hair loss on women's quality of life.
9 citations,
June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
9 citations,
March 2017 in “JAAD Case Reports” A woman's scalp condition improved with specific ointment after a hair piece caused skin issues.
9 citations,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
9 citations,
October 2012 in “Thermochimica Acta” Finasteride's two forms have different stability based on temperature and pressure.
8 citations,
May 2021 in “Journal of the European Academy of Dermatology and Venereology” A COVID-19 patient had unusual nail discoloration and nail separation possibly due to the virus's effects on small blood vessels.
8 citations,
August 2020 in “PLOS Computational Biology” A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.