9 citations
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April 2019 in “Journal of structural biology” This study found that coconut oil impedes hair hydration more effectively than soybean oil by penetrating deeper, and suggested a new model for intermediate filament assembly in hair.
8 citations
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May 2017 in “IUBMB life” This review discusses the role of astrotactins in development and their genetic mutations' links to a variety of human diseases, but reports no new clinical results.
October 2024 in “International Journal of Pharmaceutics” This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.
24 citations
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July 2017 in “Structure” In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.
Hair coloring and bleaching can permanently break down hair protein and temporarily change its properties.
9 citations
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July 2014 in “Skin research and technology” This study found that Caucasian hair is destroyed more easily than Asian hair when stretched, as indicated by changes in secondary structure, disulfide bond breakage, and physical disintegration.
9 citations
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January 1981 This study found that the alkaline degradation process of hair keratin using nucleophilic reagents led to different proportions of reaction products compared to wool, particularly more lanthionine and lysinoalanine residues.
March 2026 in “Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials” This study investigated the mechanical response of the human hair cuticle to strain and found that cuticular deformation directly corresponded with fiber elongation, revealing significant molecular-level changes in disulfide crosslinks but maintained structural stability, highlighting the role of the cuticle in stress resistance.
This review summarizes recent genetic research on hidradenitis suppurativa, highlighting potential therapeutic targets and genetic mutations, but reports no new clinical findings.
10 citations
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February 2018 in “Royal Society Open Science” This study found that a shampoo containing quaternized wheat protein hydrolysate can effectively improve hair recovery by smoothing and compacting damaged hair surfaces, thanks to modifications that enhance protein adherence and disulfide bond formation at pH levels typical in hair care products.
January 2024 in “Biochemistry Research International” This study found that compounds from Ziziphus spina-christi roots exhibited promising antibacterial and antioxidant activities, supporting its traditional medicinal use.
72 citations
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December 2009 in “Organic and Biomolecular Chemistry” This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.
1 citations
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September 2022 in “Sudan Journal of Medical Sciences” This molecular docking study reported that danoprevir, remdesivir, and saridegib exhibit stronger binding affinities to the main protease of SARS-CoV-2 than the control, suggesting their potential as inhibitors of the virus's replication process.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.
January 2013 in “Transactions of the Materials Research Society of Japan” In this study, carboxymethylalanyl disulfide keratin was shown to effectively prevent hair damage during repeated bleaching and permanent waving treatments.
82 citations
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October 2019 in “Frontiers in Immunology” This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.
March 2010 in “Cosmetic Dermatology” Hair straightening methods have advanced to improve effectiveness and reduce damage, but still rely on heat and chemicals.
5 citations
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January 2024 in “Crystals” This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.
March 2026 in “The Indian Journal of Animal Sciences” This study on Indian dromedary camel breeds investigated the KRTAP7 protein, finding all four breeds shared an identical gene sequence, with 13 phosphorylation and glycosylation sites influencing hair characteristics, alongside predicted interactions with other biosynthesis-related proteins.
August 2002 in “Analytical Sciences” The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.
January 2024 in “Research Square (Research Square)” This study identified key genes related to ischemic stroke through the ferroptosis pathway and highlighted the potential role of specific traditional Chinese medicines in regulating associated biological processes.
9 citations
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April 2018 in “Journal of trace elements in medicine and biology” This review presents the practice of using hair bioelement analysis to assess nutritional status or environmental exposure, proposing complex interactions and hypotheses regarding depression and autism but reports no new clinical results.
December 2025 in “Biopolymers” This study found that chemically treated hair, particularly when subjected to both acid straightening and bleaching, experiences more significant structural damage when exposed to heat, highlighting key changes in both the internal and surface components of hair fibers.
February 2026 in “Toxicology Letters” This study used an in silico/in vitro approach to identify potential inhibitors of the enzyme SRD5A2, finding that the androgen receptor modulator MK-0773 is a moderate inhibitor, although it does not act as a covalent inhibitor like finasteride.
33 citations
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November 2008 in “European Journal of Pharmaceutical Sciences” This study found that St. John's wort treatment for two weeks induced finasteride metabolism and reduced its plasma exposure in healthy men.
September 2024 in “Health of Man” This study reports that hyperuricemia, the second most common metabolic disease after diabetes, is linked to numerous health issues, especially in males, and recommends lifestyle modifications as an effective management strategy, highlighting the lack of consensus on uric acid thresholds necessitating drug therapy.
36 citations
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October 2014 in “Langmuir” This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.
June 2001 in “Proceedings of SPIE” The authors concluded that low energy laser therapy may serve as a useful complementary treatment for skin diseases such as lichen planus, infectious finger pulpits, scalp alopecia, and crural ulcers.
March 2010 in “International Journal of Cosmetic Science” This study found that oxidative treatment with peracetic acid dissociates some disulfide bonds in human hair fibers while maintaining the crystalline structure, suggesting different mechanisms stabilize different regions of intermediate filaments.
1514 citations
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December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.