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      Abstract 80

      research Abstract 80

      April 2017 in “Plastic and Reconstructive Surgery – Global Open”
      In this study, researchers developed a 3D-printed vascular model to analyze how different shear stresses influence cell behavior and promote cellular organization around neovessels, offering insights into tissue engineering for wound reconstruction.
      Editors' Picks

      research Editors' Picks

      September 2007 in “Journal of Investigative Dermatology”
      ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
      The Biology of Hair Follicles

      research The Biology of Hair Follicles

      1113 citations , August 1999 in “The New England Journal of Medicine”
      This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
      Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin

      research Epidermal homeostasis: a balancing act of stem cells in the skin

      1039 citations , February 2009 in “Nature Reviews Molecular Cell Biology”
      This review discusses the reuse of molecular mechanisms involved in embryonic skin development for maintaining adult epidermal homeostasis and reports no new results.
      Alginate and Its Application to Tissue Engineering

      research Alginate and its application to tissue engineering

      425 citations , January 2021 in “SN Applied Sciences”
      This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
      Wound Healing and Skin Regeneration

      research Wound Healing and Skin Regeneration

      359 citations , January 2015 in “Cold Spring Harbor Perspectives in Medicine”
      This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
      IL-17-Producing Gamma Delta T Cells Enhance Bone Regeneration

      research IL-17-producing γδ T cells enhance bone regeneration

      343 citations , March 2016 in “Nature Communications”
      This study found that IL-17A-producing γδ T cells play a key role in bone fracture healing by promoting bone formation, with deficiencies leading to impaired repair in mice.
      Stem Cells and the Niche: A Dynamic Duo

      research Stem Cells and the Niche: A Dynamic Duo

      333 citations , February 2010 in “Cell Stem Cell”
      This review discusses experimental data, technologies, and genetic factors related to stem cell niches, highlighting their role in tissue regeneration and diseases, but reports no new results.
      Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

      research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

      326 citations , February 2009 in “˜The œAmerican journal of pathology”
      This review discusses the role of Lgr5 as a marker for identifying adult stem cells, particularly in the intestine and hair follicles, and reports no clinical results.
      Recent Advances in Electrospun Nanofibers for Wound Healing

      research Recent advances in electrospun nanofibers for wound healing

      262 citations , May 2017 in “Nanomedicine”
      This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.
      Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

      research Transforming growth factor-β in stem cells and tissue homeostasis

      245 citations , January 2018 in “Bone Research”
      This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
      Tracing the Cellular Origin of Cancer

      research Tracing the cellular origin of cancer

      232 citations , January 2013 in “Nature Cell Biology”
      Understanding where cancer cells come from helps create better prevention and treatment methods.
      Microtechnology-Based Methods for Organoid Models

      research Microtechnology-based methods for organoid models

      223 citations , October 2020 in “Microsystems & Nanoengineering”
      This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.
      A Guide to Studying Human Hair Follicle Cycling In Vivo

      research A Guide to Studying Human Hair Follicle Cycling In Vivo

      212 citations , September 2015 in “Journal of Investigative Dermatology”
      This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.
      Androgens and Hair Growth

      research Androgens and hair growth

      209 citations , September 2008 in “Dermatologic Therapy”
      This review discusses the role of androgens in hair follicle regulation and suggests that a better understanding could enhance treatments for conditions like hirsutism and alopecia, but does not present new findings.
      Stem Cell Niches in Mammals

      research Stem cell niches in mammals

      205 citations , August 2007 in “Experimental Cell Research”
      This review discusses advances in understanding mammalian stem cell niches, particularly in bone marrow, tooth, and hair follicle, and highlights the potential for developing therapies targeting these niches for tissue repair.
      Bioengineering Skin Using Mechanisms of Regeneration and Repair

      research Bioengineering skin using mechanisms of regeneration and repair

      202 citations , August 2007 in “Biomaterials”
      This review discusses advancements in artificial skin for wound treatment and reports no new clinical findings; the authors highlight the potential of new biomaterials to enhance future skin replacement therapies.