November 2025 in “Frontiers in Pharmacology” This study observed that both in vitro and in vivo research demonstrated rice bran extract can significantly enhance collagen and elastin synthesis, reduce water loss, and improve skin quality and elasticity, highlighting its potential as a sustainable cosmetic ingredient.
April 2023 in “Journal of Investigative Dermatology” This study suggests that the mTOR signaling pathway may play a role in the pathophysiology of radiation dermatitis, with expression patterns of S6K1 protein differing from those in normal and inflamed skin.
November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
2 citations
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November 2017 in “PloS one” This study found that 2MbisP increases epidermal thickening more rapidly than atRA in rhino mice, while both compounds similarly reduce utricle size.
189 citations
,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” This review discusses how research on keratin biology has enhanced the understanding of epidermolysis bullosa simplex and indicates potential new therapeutic approaches, but it presents no new experimental results.
August 2024 in “Postgraduate Medical Journal” A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.
July 2024 in “Journal of Investigative Dermatology” CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
September 2024 in “Journal of Medicine and Life” In this study, researchers identified a recurrent nonsense mutation, c.409C>T (p.Arg137*), in the COL7A1 gene through whole exome sequencing in a family with autosomal recessive dystrophic epidermolysis bullosa, demonstrating the importance of this method for diagnosing genetically complex conditions.
April 2025 in “Our Dermatology Online” This article presents a case of a seventeen-year-old female with dermatopathia pigmentosa reticularis and emphasizes the importance of distinguishing its clinical features from other similar disorders, supported by dermoscopic and histopathological findings.
1 citations
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May 2024 in “Journal of Dermatological Science” In this study, KC-AD-MSCs were found to increase COL7 deposition and anchoring fibril formation at the dermal-epidermal junction in a RDEB mouse model, suggesting potential for improving skin integrity in recessive dystrophic epidermolysis bullosa patients.
52 citations
,
November 2006 in “International Journal of Cosmetic Science” This review discusses the identification and classification of different wrinkle types based on histological features and microanatomy, emphasizing their varying responses to treatments, and reports no new clinical results.
19 citations
,
October 1985 in “British Journal of Dermatology” This review proposes a new approach for categorizing and diagnosing unruly hair forms, building on previous literature and clinical experience, without presenting new clinical results.
46 citations
,
December 2018 in “Biomedical Optics Express” In this study, researchers observed that Raman spectroscopy effectively differentiates basal cell carcinoma from normal skin structures by analyzing biochemical markers, suggesting its potential as a surgical guidance tool for cancer margin resection during Mohs surgery.
January 2007 in “Bristol Research (University of Bristol)” This study diagnosed epidermolysis bullosa in eight calves across four UK farms, characterized by skin lesions and excluding mutations in keratin genes as the cause.
2 citations
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October 2023 in “PubMed” This study reported the creation of isogenic immortalized COL7A1-deficient keratinocyte lines, providing a model for researching Recessive Dystrophic Epidermolysis Bullosa biology and potential therapies.
May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
15 citations
,
January 2019 in “Experimental Dermatology” In this study, full-thickness wounding on Lanyu pigs led to scar formation and disrupted cell markers, while partial-thickness wounding allowed limited regeneration of rete ridges and papillary dermis.
1 citations
,
November 2024 in “Cureus” This case report describes a rare aggressive variant of squamous cell carcinoma on the scalp of a non-immunosuppressed older male, highlighting its high biological risk for metastasis and poor outcomes.
February 2026 in “Scientific Reports” This study established a murine model for radiation-induced skin reactions, replicating clinical and histological features to aid future mechanistic and therapeutic research.
February 2023 in “Benha Journal of Applied Sciences” This article reviews R-Spondin-1's complex role in various skin conditions, emphasizing its diagnostic, prognostic, and potential therapeutic applications.
1 citations
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January 2015 in “The Journal of Dermatology” This letter to the editor presents a case of non-Herlitz junctional epidermolysis bullosa associated with a COL17A1 mutation and reports no new clinical findings.
July 2024 in “Journal of Cosmetic Dermatology” In this clinical study, a vegan collagen builder (VEGCOL™️) was shown to safely and effectively improve hair growth, skin smoothness, wrinkle reduction, and joint pain relief in adults, with enhancements varying by dose over a 60-day period.
34 citations
,
October 1982 in “Journal of applied polymer science” This study found that the moisture content of human hair significantly influences the type of fracture under tensile loading, with low or high humidity levels leading to smooth fractures and intermediate humidity resulting in step fractures.
1 citations
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January 2025 in “Poultry Science” In this study, researchers examined skin growth and quality in Pekin ducks from 1 to 6 weeks of age, finding that skin factors like strength and collagen content increased with age and were influenced by gene expressions related to cell proliferation and collagen synthesis.
August 2022 in “Tissue Engineering Part A” This study observed that using ex vivo gene therapy to modify skin cells in a pre-graft model improved dermal-epidermal junction adhesion strength and maintained collagen production over time, suggesting a potential treatment approach for recessive dystrophic epidermolysis bullosa skin wounds.
1 citations
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April 2024 in “Lasers in Surgery and Medicine” This study developed a 3D computational model to simulate how skin, fat, and muscle deform under suction, reporting that as suction pressure increased, skin thickness decreased, while fat thickness increased, and muscle thickness remained stable, closely aligning with experimental results.
10 citations
,
April 2017 in “PLoS ONE” This study reports that the white rhinoceros has a unique integumentary structure among large herbivores, characterized by thick epidermis, organized collagen bundles, and the presence of coiled sweat glands.
34 citations
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November 2010 in “Development” In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.
14 citations
,
May 2017 in “Journal of Investigative Dermatology” This study reports a novel homozygous mutation in the DST gene causing a unique form of epidermolysis bullosa simplex with prurigo papules in a 39-year-old Syrian man.
97 citations
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March 2010 in “The American Journal of Human Genetics” A mutation in the KRT74 gene causes tightly curled hair.