Establishing a Robust Preclinical Model to Investigate Early and Late Radiation-Induced Skin Reactions

The user experienced scalp burning and diffuse hair shedding after surgery, with symptoms worsening due to factors like weather changes and stress. They tried minoxidil and finasteride but stopped due to side effects, and found some relief with corticosteroid scalp treatments while correcting vitamin deficiencies.

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.

Genetics, inflammation, poor scalp circulation, stress, thyroid issues, low iron, vitamin D deficiency, steroids, age, fungal infections, stress, and creatine can increase hair sensitivity to DHT. Treatments mentioned include dutasteride, minoxidil, and Kre Alkalyn Monohydrate.

The conversation discusses hair shedding potentially linked to vitamin D supplementation after Accutane use, with the user suspecting telogen effluvium. Others suggest the hair loss might not be related to vitamin D, considering it a coincidence.