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Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

PGD2 stops hair growth and is higher in bald men with AGA.

Some medicinal plants can help heal wounds and may lead to new treatments.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.