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The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Stem cell niches support, regulate, and coordinate stem cell functions.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

Mutant mice help researchers understand hair growth and related genetic factors.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The most common skin problems in Indian children are infections and eczemas.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Some breast cancer patients still experience hair loss three years after chemotherapy, especially with taxane-based treatments.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.