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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Mutant mice help researchers understand hair growth and related genetic factors.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

New treatments for male hypogonadism are effective and should be personalized.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

No cure for female pattern hair loss, but various effective treatments exist.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.