January 2015 in “Elsevier eBooks” This study suggests that targeting the endocannabinoid system through pharmacological interventions may help reduce compulsive hair-pulling in individuals with trichotillomania.
In this review, researchers analyzed literature on trichotillomania and found advances in understanding its neurobiology—highlighting dysregulated reward circuits and genetics—and treatments, with behavioral therapy and innovative pharmacological approaches improving outcomes where traditional SSRIs do not.
September 2016 in “한국임상약학회지” In this study, ibuprofen, menthol, and cetirizine were found to potentially prevent or slow down damage to human dermal fibroblast cells caused by intermittent fever in early alopecia.
119 citations
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February 2009 in “Neuroscience & Biobehavioral Reviews” This review discusses the psychological and neurobiological aspects of trichotillomania and reports no new results, emphasizing the need for further research on its treatment and neural mechanisms.
3 citations
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May 2018 in “Psychiatry and Clinical Psychopharmacology” In this report, an 18-year-old female with trichotillomania was successfully treated using the glutamate modulator n-acetylcysteine.
3 citations
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April 2011 in “Neuropsychiatry” This review discusses the potential factors contributing to trichotillomania and reports that behavioral therapy, N-acetyl cysteine, and olanzapine may be beneficial for those affected; it provides no new clinical results.
February 2025 in “International Journal of Clinical & Experimental Dermatology” In this study, trichoscopy was identified as an effective tool for diagnosing trichotillomania in children, and a multidisciplinary, individualized approach along with family support was deemed essential for managing the condition and achieving sustained remission.
January 2022 in “Clinical Cases in Dermatology” This review discusses prevention, diagnosis, and treatment strategies for traction alopecia but presents no new clinical findings; the authors emphasize early intervention to prevent permanent hair loss.
January 2018 in “Springer eBooks” Trichotillomania is a condition where people repeatedly pull out their hair, which can be triggered by stress and has various physical signs.
February 2023 in “Journal of The American Academy of Dermatology” This publication discusses the use of low-dose oral minoxidil for treating traction alopecia but reports no new clinical outcomes; further research on its efficacy and safety is needed.
In this literature review, researchers highlighted that trichotillomania involves dysregulated reward circuits, abnormal sensory processing, and potential genetic factors, advancing both therapeutic strategies and understanding of the condition, but stigma and provider training gaps persist in effective care provision.
November 2023 in “Scholars academic journal of biosciences” This study highlights a case of trichotillomania with trichophagia in a 7-year-old girl, illustrating the medical complications and need for awareness and collaborative management of this condition, often misdiagnosed due to stigma.
May 2022 in “European medical journal” This case report highlights a rare instance of gastric trichobezoar, or "Rapunzel syndrome," associated with trichotillomania, characterized by hair accumulation in the stomach of a patient.
April 2016 in “Apollo (University of Cambridge)” This article reviews treatment approaches for trichotillomania, emphasizing differences from OCD therapies and recommending specific management strategies, without providing new experimental findings.
29 citations
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February 2019 in “Pediatric dermatology” This abstract suggests that specific trichoscopic features like black dots, coiled hair, and trichoptilosis may help differentiate trichotillomania from patchy alopecia areata.
1 citations
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September 2024 in “iScience” In a study on mice, researchers found that exposure to artificial light environments causing circadian misalignment impaired hair growth by reducing the hair growth rate during the anagen phase, suggesting these light conditions as a potential risk factor for hair loss.
September 2017 in “OhioLink ETD Center (Ohio Library and Information Network)” In this study, dementia caregivers showed lower hair cortisol levels than controls despite reporting higher perceived stress, providing weak support for the Perseverative Cognition Hypothesis and suggesting complex effects of caregiving stress.
May 2017 in “InTech eBooks” This review discusses trichotillomania and traction alopecia, focusing on their clinical features, diagnostic criteria, and treatment options, but it reports no new research findings.
52 citations
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October 1997 in “American Journal of Psychiatry” This discussion reviews the complexities of trichotillomania's symptoms, pathology, and treatment, but reports no new research findings; it highlights a specific illustrative case.
30 citations
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January 2014 in “Dermatologic Clinics” This review discusses traction alopecia in individuals with Afro-textured hair and emphasizes the importance of education to prevent this condition, but it reports no new clinical results.
30 citations
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March 2009 in “Journal of the European Academy of Dermatology and Venereology” This article describes petechiae on the fingertips as a presenting symptom of dermatitis herpetiformis but reports no new clinical results.
17 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This study found that genes in the human keratin-associated protein 1 family may have evolved mainly through gene duplication of cysteine-repeat motifs.
3 citations
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January 2018 in “Skin Appendage Disorders” This case report describes two instances of habit tic nail deformities associated with alopecia areata.
1 citations
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July 2024 in “Cutis” This paper highlights that traction alopecia is common among certain ethnic groups and occupations due to tight hairstyling practices, but early-stage hair loss can often be reversed with treatment and by avoiding these styling habits, as observed in Hispanic and Black women.
1 citations
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December 2021 in “Daehan hwa'sang haghoeji” This article reviews the use of a latissimus dorsi musculocutaneous flap for treating chronic osteomyelitis of cranial bones following high-voltage electrical burn injuries on the scalp, but reports no new results.
April 2026 in “Current Opinion in Genetics & Development” This mini-review explores how both endogenous and damage-released RNAs serve as instructional signals that influence cell identity and plasticity during tissue maintenance and repair, highlighting RNA's role as a regulator of cellular flexibility in various regenerative contexts.
August 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This paper reviews three cases of traumatic anserine folliculosis in children, showing the condition's association with postural habits and potential improvement through posture correction and topical treatments.
This review concluded that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage and promoting cancer development and metastasis from stem cell origins.
This review concludes that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage that promotes cancer development and metastasis, by affecting normal stem cells, cancer stem cells, and cancer cells.
This review highlights that chronic inflammation leads to ongoing activation of stem cells, causing DNA damage accumulation, which can promote cancer development and metastasis.