Chronic Circadian Misalignment Is a Risk Factor for Hair Growth Impairment

    September 2024 in “ iScience
    Yoshiki Miyawaki, Atsuhiro Nishida, Keisuke Fukushima, Aoi Matsumoto, Teruki Hamano, Yukiya Mori, Mamoru Nagano, Isao T. Tokuda, Yasufumi Shigeyoshi, Koichi Node, Makoto Akashi
    TLDR Disrupted sleep patterns from artificial light can slow hair growth and may lead to hair loss.
    The study investigated the impact of modern artificial and aberrant light environments on hair growth by inducing chronic circadian misalignment in mice through repetitive light-dark reversal. Results showed that male mice with dorsal hair sheared experienced impaired hair growth under these conditions. Both male and female mice exhibited a decreased hair growth rate during the anagen phase when exposed to this light condition. Additionally, an ex vivo culture of whisker hair follicles from male mice confirmed the reduced hair growth rate. These findings suggest that chronic circadian misalignment due to artificial light environments can impair hair growth and may be a risk factor for hair loss.
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